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A promising approach for COVID-19 prophylaxis

SARS-CoV-2 viruses can hide from recognition by the immune system. However, the antiviral immune receptor RIG-I can be stimulated, which improves protection against lethal SARS-CoV-2 infections.

Nordrhein westfalenRegion flamandeSamira marxHiroki katoEva bartokGunther hartmannMartin schleeEmily hendersonInstitute of virologyMildred scheel school of oncologyInstitute of tropical medicineGerman centerUniversity hospital bonnInstitute of cardiovascular immunologyInfection researchGerman research foundation

One Of The Weirdest Resident Evil Games Is Getting An Unofficial 3D Remake

Not to be outdone by its more respected siblings, the handheld Resident Evil Gaiden is being remade by a group of independent developers. Project

United kingdomBarry burtonShinji mikamiHiroki katoResident evil gaidenGame boy colourResident evilEvil codeLeon kennedyProject starlight

New system for targeted cancer radiation therapy using gold nanoparticles

Scientists from the Department of Nuclear Medicine and Tracer Kinetics at Osaka University developed a novel system for targeted cancer radiation therapy that uses gold nanoparticles labeled with astatine-211.

Hiroki katoKoichi fukaseEmily hendersonOsaka universityTracer kinetics at osaka universityDepartment of nuclear medicineNuclear medicineTracer kineticsStudy first authorGold nanoparticlesNuclear medicineRadiation therapy

New promising antibodies against SARS-CoV-2

E-Mail IMAGE: Cell culture plates with stained cells, in which virus replication can be quantified by the ‚holes that virus infection causes in the cell lawn. view more Credit: © Volker Lannert/ University of Bonn Antibodies are an important weapon in the immune system s defense against infections. They bind to the surface structures of bacteria or viruses and prevent their replication. One strategy in the fight against disease is therefore to produce effective antibodies in large quantities and inject them into the patients. The outgoing US President Donald Trump probably owes his rapid recovery to this method. However, the antibodies used to treat him have a complex structure, do not penetrate very deeply into the tissue and may cause unwanted complications. Moreover, producing antibodies is difficult and time-consuming. They are therefore probably not suitable for widespread use.

United statesNordrhein westfalenLea marie jensterMatthias geyerYonasm tesfamariamDonald trumpJenniferd wuerthFloriann gohrJonathan leo schmid burgkLisadj schiffelersKerstinu ludwigSabine normannCarolinei fandreyMichael schindlerHiroki katoProvendis gmb

New small antibodies show promising effects against COVID-19 infection

Researchers have stitched together nanobodies (green and red) that bind to two different places on the spike protein of SARS-CoV-2. Image by Hrishikesh.

United statesNordrhein westfalenLea marie jensterMatthias geyerYonasm tesfamariamJenniferd wuerthFloriann gohrJonathan leo schmid burgkLisadj schiffelersKerstinu ludwigUlf sirborn martinSabine normannCarolinei fandreyMichael schindlerHiroki katoHejun liu

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