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A promising approach for COVID-19 prophylaxis

SARS-CoV-2 viruses can hide from recognition by the immune system. However, the antiviral immune receptor RIG-I can be stimulated, which improves protection against lethal SARS-CoV-2 infections. ....

Nordrhein Westfalen , Region Flamande , Samira Marx , Hiroki Kato , Eva Bartok , Gunther Hartmann , Martin Schlee , Emily Henderson , Institute Of Virology , Mildred Scheel School Of Oncology , Institute Of Tropical Medicine , German Center , University Hospital Bonn , Institute Of Cardiovascular Immunology , Infection Research , German Research Foundation , University Of Bonn , Institute Of Clinical Chemistry , Clinical Chemistry , Clinical Pharmacology , University Hospital , Phd Student , Angiotensin Converting Enzyme , Cardiovascular Immunology , Excellence Immunosensation , Mildred Scheel School ,

One Of The Weirdest Resident Evil Games Is Getting An Unofficial 3D Remake

Not to be outdone by its more respected siblings, the handheld Resident Evil Gaiden is being remade by a group of independent developers. Project ....

United Kingdom , Barry Burton , Shinji Mikami , Hiroki Kato , Resident Evil Gaiden , Game Boy Colour , Resident Evil , Evil Code , Leon Kennedy , Project Starlight ,

New system for targeted cancer radiation therapy using gold nanoparticles

Scientists from the Department of Nuclear Medicine and Tracer Kinetics at Osaka University developed a novel system for targeted cancer radiation therapy that uses gold nanoparticles labeled with astatine-211. ....

Hiroki Kato , Koichi Fukase , Emily Henderson , Osaka University , Tracer Kinetics At Osaka University , Department Of Nuclear Medicine , Nuclear Medicine , Tracer Kinetics , Study First Author , Gold Nanoparticles , Nuclear Medicine , Radiation Therapy ,

New promising antibodies against SARS-CoV-2

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IMAGE: Cell culture plates with stained cells, in which virus replication can be quantified by the ‚holes that virus infection causes in the cell lawn.
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Credit: © Volker Lannert/ University of Bonn
Antibodies are an important weapon in the immune system s defense against infections. They bind to the surface structures of bacteria or viruses and prevent their replication. One strategy in the fight against disease is therefore to produce effective antibodies in large quantities and inject them into the patients. The outgoing US President Donald Trump probably owes his rapid recovery to this method. However, the antibodies used to treat him have a complex structure, do not penetrate very deeply into the tissue and may cause unwanted complications. Moreover, producing antibodies is difficult and time-consuming. They are therefore probably not suitable for widespread use. ....

United States , Nordrhein Westfalen , Lea Marie Jenster , Matthias Geyer , Yonasm Tesfamariam , Donald Trump , Jenniferd Wuerth , Floriann Gohr , Jonathan Leo Schmid Burgk , Lisadj Schiffelers , Kerstinu Ludwig , Sabine Normann , Carolinei Fandrey , Michael Schindler , Hiroki Kato , Provendis Gmb , Emmy Noether , Hejun Liu , Mariah Christensen , Hrishikesh Das , Natalia Ruetalo , Karolinska Institutet , Tiana Wilson , Leo Hanke , Nicholas Wu , Floriani Schmidt ,

New small antibodies show promising effects against COVID-19 infection

Researchers have stitched together nanobodies (green and red) that bind to two different places on the spike protein of SARS-CoV-2. Image by Hrishikesh. ....

United States , Nordrhein Westfalen , Lea Marie Jenster , Matthias Geyer , Yonasm Tesfamariam , Jenniferd Wuerth , Floriann Gohr , Jonathan Leo Schmid Burgk , Lisadj Schiffelers , Kerstinu Ludwig , Ulf Sirborn Martin , Sabine Normann , Carolinei Fandrey , Michael Schindler , Hiroki Kato , Hejun Liu , Mariah Christensen , Hrishikesh Das , Natalia Ruetalo , Karolinska Institutet , Tiana Wilson , Leo Hanke , Floriani Schmidt , Steffen Pritzl , Karl Gatterdam , Nicholasc Wu ,