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Breakthrough gene therapy method utilizes bird retrotransposon for safe gene insertion

The recent approval of a CRISPR-Cas9 therapy for sickle cell disease demonstrates that gene editing tools can do a superb job knocking out genes to cure hereditary disease.

Berkeley , California , United-states , Briana-van-treeck , Van-treeck , Jeremy-mcintyre , Eva-nogales , Akanksha-thawani , Justin-shumate , Connor-horton , Kathleen-collins , Xiaozhu-zhang

Could a single synthetic molecule outsmart a variety of drug-resistant bacteria?

Scientists have created a synthetic molecule that appears capable of attacking a broad range of bacteria that have become dangerously resistant to workhorse medicines.

United-kingdom , Germany , Los-angeles , California , United-states , Canada , Yury-polikanov , Richard-alm , Andrew-myers , University-of-illinois-at-chicago , Boston-university , Us-centers-for-disease

New discovery unveils an additional layer of the CRISPR-Cas antiviral defense system

The recent publication in Science by Mogila, Tamulaitiene et al. represents a continuation of the successful scientific research conducted by Gintautas Tamulaitis' group.

Lithuania , Vilnius , Vilniaus-apskritis , Konstanty-keda , Irmantas-mogila , Albertas-timinskas , Giedrius-sasnauskas , Gintautas-tamulaitis , Giedre-tamulaitiene , Gintautas-tamulaiti , Virginijus-siksnys , Vilnius-university

Researchers study how cells adapt to stressful and complex environments

Imagine the life of a yeast cell, floating around the kitchen in a spore that eventually lands on a bowl of grapes. Life is good: food for days, at least until someone notices the rotting fruit and throws them out.

Lily-ramsey , David-pincus , Rania-garde , Kathleena-davis , Allisonh-squires , Oliviac-schaffer , Mayag-igarashi , Asif-ali , Kabir-husain , D-allan-drummond , Jaredam-bard , Samantha-keyport-kik

Stress-induced ribosome dysregulation may underlie depression

A group of ribosomal protein genes connects animal models of depression to human patients with major depressive disorder.

Xiaolu-zhang , Danielle-ellis , Mahmoud-ali-eladawi , Depression , Ibosome , Epressive-disorder , Ene , Enes , Ajor-depressive-disorder , Rotein , Tress

Antibiotics can sometimes benefit bacteria

Scientists have found a surprising effect of some antibiotics on certain bacteria – that the drugs can sometimes benefit bacteria, helping them live longer.

Robert-beardmore , Emily-wood , Danielle-ellis , University-of-exeter , Bacteria , Ntibiotic , Ntibiotic-resistance , Rugs , Utrients , Esearch , Ibosome ,

Stowers researchers reveal why certain anti-cancer drugs can cause unexpected side effects

With around 90% of drugs failing to make it to market, the potential for improving efficiency within the drug development industry is clear. Drugs designed to combat cancers suffer similar rates of failure for many reasons.

David-schneider , Laurence-florens , Juliana-conkright-fincham , Jennifer-gerton , Jay-unruh , Tamara-potapova , Lily-ramsey , Stowers-institute-for-medical-research , Stowers-institute , Medical-research , Investigator-jennifer-gerton , Cancer

Researchers discover how ribosomes regulate protein production

The human body consists of numerous trillions of cells, and 60 percent of the energy used within a cell is dedicated to a specific molecular machine.

Copenhagen , Køavn- , Denmark , Andersh-lund , Danielle-ellis , Biotech-research , Innovation-centre , University-of-copenhagen , Cancer , Ell , Enetic , Enome

The universal role of Nsp1: Common mechanisms of translational shutdown by coronaviruses

Researchers investigate Nsp1 from SARS-CoV-2, MERS-CoV, and Bat-Hp-CoV using biophysical, structural, and biochemical assays.

Middle-east , Image-credit , Bat-hp-cov-nsp , Coronavirus-disease-covid-19 , Oronavirus , Enome , Ers-cov , Rotein , Rotein-synthesis , Espiratory , Ibosome

Mutation in a ribosomal protein leads to impaired cardiac contractility in mice

A team of researchers have discovered that a mutation in a ribosomal protein found specifically in heart and skeletal muscle leads to impaired cardiac contractility in mice.

Keiichii-nakayama , Lily-ramsey , Kyushu-university-medical-institute-of-bioregulation , Nature-communications , Ribosome-heterogeneity , Kyushu-university , Medical-institute , Heart , Lanine , Trial-fibrillation , Ardiomyopathy , Ell