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With the east coast of Australia being hit with torrential rain over the past few weeks, health experts have warned about the dangers of mould growing in humid conditions.
/PRNewswire/ -- The Prostate Cancer Foundation (PCF) today announced the 2021 Class of PCF Team Challenge Award recipients and a total of more than $9 million...
/PRNewswire/ -- The Prostate Cancer Foundation (PCF) today announced the 2021 Class of PCF Team Challenge Award recipients and a total of more than $9 million...
Exploring the expression change of long-noncoding RNA CASC2 in childhood asthma and its role in airway smooth muscle cell proliferation and migration. Read more
Buruli ulcer (BU), caused by Mycobacterium ulcerans, is a devastating necrotizing skin disease. Key to its pathogenesis is mycolactone, the exotoxin virulence factor that is both immunosuppressive and cytotoxic. The discovery that the essential Sec61 translocon is the major cellular target of mycolactone explains much of the disease pathology, including the immune blockade. Sec61 inhibition leads to a loss in production of nearly all cytokines from monocytes, macrophages, dendritic cells and T cells, as well as antigen presentation pathway proteins and costimulatory molecules. However, there h...