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Largest ever genetic study of epilepsy provides new insights

The study has discovered specific changes in our DNA that increase the risk of developing epilepsy, advancing our knowledge of why epilepsy develops. ....

United-states , Australia , America , Gianpiero-cavalleri , Colin-doherty , Helen-cross , International-league-against-epilepsy , University-of-medicine , Health-sciences , Futureneuro-research-centre , Futureneuro-centre , Consortium-on-complex-epilepsies

Management of epilepsy during pregnancy and lactation

Epilepsy is a group of neurological diseases characterized by susceptibility to recurrent seizures. Antiseizure medications (ASMs) are the mainstay of treatment, but many antiseizure medications with variable safety profiles have been approved for use. For women with epilepsy in their childbearing years, the safety profile is important for them and their unborn children, because treatment is often required to protect them from seizures during pregnancy and lactation. Since no large randomized controlled trials have investigated safety in this subgroup of people with epilepsy, pregnancy registries, cohort and case-control studies from population registries, and a few large prospective cohort studies have played an important role. Valproate, in monotherapy and polytherapy, has been associated with elevated risk of major congenital malformations and neurodevelopmental disorders in children born to mothers who took it. Topiramate and phenobarbital are also associated with elevated risks of ....

Nairobi , Nairobi-area , Kenya , United-kingdom , United-states , Norway , Australia , Denmark , Iceland , Kuopio , Norra-savolax , Finland

Can Early EEG Monitoring Be a Good Predictive Tool for Children With Epilepsy?

Two abstracts presented at the 2023 International Epilepsy Congress evaluated early electroencephalography (EEG) monitoring in children with seizures and encephalopathy. ....

Ireland , Dublin , International-epilepsy-congress , International-league-against-epilepsy , Epilepsy , Eeg , Children-with-encephalopathy , First-unprovoked-seizures ,

International Epilepsy Congress takes place in Dublin

The largest scientific epilepsy meeting in the world is taking place in Dublin this month. Ireland hosts the International Epilepsy Congress (IEC) for the ....

Dublin , Ireland , Irish , International-league-against-epilepsy , Dublin-convention-centre , International-epilepsy-congress , International-bureau-for-epilepsy , International-bureau ,

Largest genetic analysis of epilepsy reveals 26 risk regions in DNA

A large-scale genetic study found 26 risk loci for epilepsy, a chronic brain disease with multiple forms, not all of them heritable. The work, by more than 300 authors from the International League Against Epilepsy (ILAE), investigated 7 different subtypes of this neurological condition. ....

Gianpiero-cavalleri , International-league-against-epilepsy , Epilepsy , Risk-loci ,