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A targeted genetic sequencing strategy effectively identified homologous recombination DNA repair deficiency in ovarian cancer patients, and may eventually help predict treatment response.
A blood biomarker that measures astrocyte reactivity may help determine who, among cognitively unimpaired older adults with amyloid-beta, will go on to develop Alzheimer's disease, new research suggests.
Triple switching from infliximab biologic to biosimilar for IBD found no new safety or efficacy concerns.
The B vitamin L-methylfolate is a promising adjunct for depression in patients with an inadequate response to antidepressants, particularly in those with high inflammatory biomarkers or obesity.
Dual orexin receptor antagonists -- currently approved for insomnia -- may also be effective for REM sleep behavior disorder.