Index Identifies Subclinical Heart Failure Risk in Type 2 Diabetes
The triglyceride-glucose index correlated with subclinical heart failure with preserved ejection fraction in asymptomatic patients with type 2 diabetes.
Source: medscape.com
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Red Blood Cells Made to Deliver Antibiotics to Bacteria
A “smart blood” platform delivered antibiotics to E coli without harming normal cells.
Source: medscape.com
Olpasiran Provides Large Sustained Cut in Lp(a): OCEAN(a)-DOSE
The small interfering RNA product showed reductions of more than 95% in levels of Lp(a) at doses of 75 mg or more when given every 12 weeks in a new phase 2 study.
Source: medscape.com
Triglyceride Lowering Fails to Show CV Benefit in Large Fibrate Trial
In the phase 3 PROMINENT trial, pemafibrate improved multiple lipid fractions in patients with type 2 diabetes, without any impact on cardiovascular events.
Source: medscape.com
New Trial Suggests CV Benefit With EPA: RESPECT-EPA
Although the open-label trial has many limitations, it could add some support to findings from the REDUCE-IT study, which showed a reduction in cardiovascular events with high-dose eicosapentaenoic acid.
Source: medscape.com