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How Do Newer Antidiabetic Drugs Lower Stroke Risk?

Studies suggest that lower stroke risk associated with newer antidiabetic therapies is not due to the drugs' tighter glycemic control. So, what is the mechanism?

Shawnee , Kansas , United-states , University-of-kentucky , Kentucky , Denver , Colorado , American , Gordon-kelley , Larryb-goldstein , University-of-kentucky-college-medicine , American-college-of-cardiology-heart-association

Delta Wave Sleep Disruption Linked to Increased CV Risk

Delta wave activity disruption during sleep may be a useful metric to identify those at an increased risk for cardiovascular disease and mortality, a new study suggested.

Guangzhou , Guangdong , China , Boston , Massachusetts , United-states , Tianyi-huang , Guangzhou-medical-university , Journal-of-the-american-college-cardiology , Heart-health-study , Sleep-heart-health-study , Osteoporotic-fractures

Prurigo Nodularis Associated With Elevated CV Risks

"The potential risk of subsequent cardiovascular disease should be considered in the care of patients with PN," according to the study authors.

Germany , Henning-olbrich , Department-of-dermatology , Global-collaborative-network-of-trinet , Global-collaborative-network , Cv-risk , Ardiovascular-risk , V-risk-factors , Ardiovascular-risk-factors , Ardiovascular-risk-management , Atherosclerotic-heart-disease , Therosclerotic-cardiovascular-disease

What Happened to Aspirin? And What Replaces It?

Although low-dose aspirin to reduce the risk for first-time heart attacks and strokes was the standard of care for 30 years, the risk-benefit calculation has changed.

United-states , Boston , Massachusetts , Houston , Texas , Americans , American , Muhammad-maqsood , John-wong , American-heart-association , American-college-of-cardiology , Us-preventive-services-task-force

Heart Failure, Not Stroke, Most Common Complication of A-Fib

A new study found the lifetime risks of post-AF stroke, ischemic stroke, and myocardial infarction improved remained high, with virtually no improvement in the lifetime risk for heart failure.

Texas , United-states , Aalborg , Nordjylland , Denmark , Danish , Johnp-higgins , Jianhua-wu , Mcgovern-medical-school , Department-of-clinical-medicine-at-aalborg-university , Health-service-research , Danish-center

Extended Zerlasiran Data Show Sustained Lp(a) Reduction

The experimental siRNA agent led to prolonged Lp(a) reduction of more than 90%, extended data from the phase 1 trial show, supporting the move to phases 2 and 3 trials.

New-york , United-states , Cleveland , Ohio , Stevene-nissen , Roberts-rosenson , Icahn-school-of-medicine-at-mount-sinai , Cleveland-clinic , Silence-therapeutics , Icahn-school , Mount-sinai

Coronary Sinus Reducer an Option for Intractable Angina?

A coronary sinus reducer met one of two primary endpoints by reducing refractory angina in the ORBITA-COSMIC trial, but not the second, improvement in perfusion.

London , City-of , United-kingdom , Cincinnati , Ohio , United-states , North-carolina , Canada , Duke-university , Canadian , Michaelj-foley , Jennifera-rymer

Preventive PCI for Vulnerable Plaques Reduces Cardiac Events

Preventive PCI plus optimal medical therapy reduced cardiac events and death in patients with non–flow-limiting coronary plaques vs medical therapy.

Seoul , Soult-ukpyolsi , South-korea , Croatia , New-york , United-states , New-zealand , Taiwan , The-mount , New-zealand-general- , Japan , Republic-of-korea

Substantial Triglyceride Reduction With Plozasiran

In patients with severe hypertriglyceridemia who are at risk for acute pancreatitis, the drug brought about triglyceride reductions of more than 50% in the phase 2 SHASTA-2 study.

Georgia , United-states , Canada , Montreal , Quebec , North-carolina , Atlanta , Neha-pagidipati , Daniel-gaudet , University-of-montreal , American-college-of-cardiology-annual-scientific-session , Duke-clinical-research-institute

Dollars, Points Help CV Patients Increase Activity

Modest financial incentives and gamification encouraged people with cardiovascular risks to meaningfully increase daily step counts over 18 months, in the BE ACTIVE trial.

University-of-pennsylvania , Pennsylvania , United-states , Philadelphia , Illinois , Riga , Latvia , Alexanderc-fanaroff , Centers-for-disease , American-college-of-cardiology , American-college