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Cancer Vaccine Could Go 'Above and Beyond Standard of Care' For Patients

Moderna and Merck have initiated V940-001, a phase 3 study evaluating vaccine mRNA-4157 and anti-PD-1 therapy Keytruda as postsurgical treatment for stage 2B to 4 melanoma. ....

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Dr Weber on the Background of the KEYNOTE-942 Trial in High-Risk Melanoma

Jeffrey S. Weber, MD, PhD, discusses the background for the KEYNOTE-942 trial, which was conducted in resected high-risk melanoma. ....

Jeffreys Weber , Grossman School Of Medicine , Melanoma Research Program , Langone Perlmutter Cancer Center , York University , New York University , Isaac Perlmutter Professor , Nyu Langone X27s Perlmutter Cancer Center , Onclive Tv , Skin Cancer ,

ctDNA Patterns May Predict Outcomes Achieved With mRNA-4157 Plus Pembrolizumab in High-Risk Melanoma

Jeffrey S. Weber, MD, PhD, highlighted key efficacy findings from the mRNA-4157-P201/KEYNOTE-942 trial, expanded on the potential utility of longitudinal ctDNA dynamics as a kinetic marker for clinical outcomes in melanoma, and underscored the importance of continued research on mRNA vaccines paired with standard PD-1 therapy across cancer types. ....

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World-Renowned Surgeon Named New Director of Moores Cancer Center at UC San Diego Health

Diana M. Simeone, MD, has been named the new director of Moores Cancer Center at UC San Diego Health. ....

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Simeone and Fakih Detail Research Objectives With A2B530 in CEA-Expressing Solid Tumors

Drs Simeone and Fakih discuss the main objective and design of the observational BASECAMP-1 study and how it functions alongside the EVEREST-1 study, which is evaluating the autologous CAR T-cell therapy A2B530 in patients with CEA-expressing solid tumors that have lost HLA-A 02 expression. ....

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