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New technique to hyperpolarize and purify fumarate for MRI A promising new concept published by an interdisciplinary research team in "Proceedings of the National Academy of Sciences" (PNAS) paves the way for major advances in the field of magnetic resonance imaging (MRI). Their new technique could significantly simplify hyperpolarized MRI, which developed around 20 years ago for observing metabolic processes in the body. The proposal involves the hyperpolarization of the metabolic product fumarate using parahydrogen and the subsequent purification of the metabolite. "This technique would no...

A promising new concept presented by an interdisciplinary research team paves the way for major advances in the field of magnetic resonance imaging (MRI). Their new technique could significantly simplify hyperpolarized MRI. The proposal involves the hyperpolarization of the metabolic product fumarate using parahydrogen and the subsequent purification of the metabolite.

 E-Mail IMAGE: The phantom used for hyperpolarized imaging, with an illustration of imaging slices acquired using the new technique. view more  Credit: photo/©: Laurynas Dagys, University of Southampton Magnetic resonance imaging (MRI) is already widely used in medicine for diagnostic purposes. Hyperpolarized MRI is a more recent development and its research and application potential has yet to be fully explored. Researchers at Johannes Gutenberg University Mainz (JGU) and the Helmholtz Institute Mainz (HIM) have now unveiled a new technique for observing metabolic processes in the...