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Urine Test Bypasses the Need for Prostate Biopsies | Clinical And Molecular Dx

Researchers have created a urine test for prostate cancer that could make unnecessary biopsies a thing of the past. The high-performing diagnostic accurate | Clinical And Molecular Dx ....

United States , Jeffrey Tosoian , University Of Michigan , ஒன்றுபட்டது மாநிலங்களில் , பல்கலைக்கழகம் ஆஃப் மிச்சிகன் ,

Urine test accurately flags prostate cancer


Researchers have found that a new urine test is extremely accurate at detecting aggressive prostate cancer with few false negatives.
The test could have possibly avoided one third of unnecessary prostate cancer biopsies while failing to detect only a small number of cancers, according to a validation study of more than 1,500 patients.
The MyProstateScore test measures levels of cancer-specific genes in a patient’s urine. It’s based on previous research that discovered half of all prostate tumors harbor a certain genetic anomaly in which the genes TMPRSS2 and ERG relocate on a chromosome and fuse together creating an on-switch for prostate cancer development. ....

United States , Jeffrey Tosoian , Johns Hopkins University , National Institutes Of Health , Fred Hutchinson Cancer Research Institute , Prostate Cancer Foundation , A Alfred Taubman Medical Research Institute , University Of Michigan , National Institutes , Taubman Medical Research Institute , ஒன்றுபட்டது மாநிலங்களில் , ஜான்ஸ் ஹாப்கின்ஸ் பல்கலைக்கழகம் , தேசிய நிறுவனங்கள் ஆஃப் ஆரோக்கியம் , ஃப்ரெட் ஹட்சின்சன் புற்றுநோய் ஆராய்ச்சி நிறுவனம் , ப்ராஸ்டேட் புற்றுநோய் அடித்தளம் , பல்கலைக்கழகம் ஆஃப் மிச்சிகன் , தேசிய நிறுவனங்கள் , டௌப்மந் மருத்துவ ஆராய்ச்சி நிறுவனம் ,

Study: New prostate cancer test could avoid unnecessary biopsies


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A urine test based on University of Michigan Rogel Cancer Center research could have avoided one third of unnecessary prostate cancer biopsies while failing to detect only a small number of cancers, according to a validation study that included more than 1,500 patients. The findings appear in the March issue of the
Journal of Urology.
The MyProstateScore test, which is being commercialized by LynxDX, a U-M startup company, measures levels of cancer-specific genes in a patient s urine. It is based on U-M research that discovered that half of all prostate tumors harbor a certain genetic anomaly in which the genes TMPRSS2 and ERG relocate on a chromosome and fuse together creating an on-switch for prostate cancer development. ....

United States , Nicholasw Eyrich , Rachel Botbyl , Gary Longton , Javed Siddiqui , Scotta Tomlins , Balaji Pandian , Zoey Chopra , Yashars Niknafs , Lakshmip Kunju , Toddm Morgan , Johnt Wei , Ganeshs Palapattu , Yingye Zheng , Daniele Spratt , Jeffrey Tosoian , Brucej Trock , Johns Hopkins University , National Cancer Institute Prostate , A Alfred Taubman Medical Research Institute , Early Detection Research Network , Um Precision Health Research Scholar Award , University Of Michigan Rogel Cancer Center , Fred Hutchinson Cancer Research Institute , Prostate Cancer Foundation , Career Enhancement Program ,