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Benzene Exposure Leads to Lipodystrophy and Alters Endocrine Activity In Vivo and In Vitro

Benzene Exposure Leads to Lipodystrophy and Alters Endocrine Activity In Vivo and In Vitro
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United States , Miami Lakes , Santa Clara , Tsingke Biotechnology Co Ltd , International Agency For Research On Cancer , Sun Yat Sen University , Biotechnology Co Ltd , National Natural Science Foundation Of China , Laboratory Animal Ethics Committee , National Institutes Of Health , Jiancheng Bioengineering Institute , Suzhou Niumag Analytical Instrument Corporation , School Of Public Health , Takara Biotechnology Co Ltd , International Agency , Liaoning Changsheng Biotechnology , Drew Scientific , Nanjing Jiancheng Bioengineering Institute , State Science , Technology Commission , Urinarys Phenylmercapturic Acid , Routine Test , Composition Analysis , Body Fat , National Institutes , Quantum Studio ,

Vancomycin induced ferroptosis in renal injury

Investigating the mechanism of Vancomycin -overdose-induced kidney injury ....

United States , Zhong Qiao Xin Zhou , Laboratory Animals , Ethics Committee , Jiancheng Bioengineering Institute , Animal Care , Use Committee , Animal Management , Shanghai Children , National Institutes , Health Guide , Ultra Vision Quanto Detection System , Thermo Scientific , Shanghai Zhong Qiao Xin Zhou Biotechnology , Flow Cytometry , Annexinv Fluorescein , Protein Extraction , Super Signal West Pico , Green Real Time , Linked Immunosorbent Assay , Nanjing Jiancheng Bioengineering Institute ,

Mechanism of oral nanomedicines & 6-MPNs

The present study aims to explain the uptake and trafficking mechanism for 6-mercaptopurine nanomedicines we previously constructed. ....

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The protective effects of sodium tanshinone IIA sulfonate

Whether STS plays a protective role in AS by regulating endothelial cell mitochondrial function and pyroptosis through an AMPK-dependent mitochondrial pathway. ....

United States , United Kingdom , Nano Zoomer Hamamatsu , Dojindo Kumamoto , Huvecs Lonza , Clinx Chemiscope , Care Of Laboratory Animals , Drug Administration , Jiancheng Bioengineering Institute , Ethics Committee Of Zhejiang Chinese Medical University , Cell Signaling Technology , Oil Redo Solarbio , Gempharmatech Co Ltd , Chinese State Food , Chinese Regulation , Medical Code , Ethics Committee , Zhejiang Chinese Medical University , Santa Cruz , Nano Zoomer , Staining Kit , Mitochondrial Membrane Potential , Mito Tracker Green , Thermo Fisher Scientific , Mitosox Red , Micro Confocal High Content Imaging System ,

Echinococcus granulosus sensu stricto and antigen B may decrease inflammatory bowel disease through regulation of M1/2 polarization | Parasites & Vectors

Inflammatory bowel disease (IBD) is a chronic idiopathic disease characterized by inflammation-related epithelial barrier damage in the intestinal tract. Helminth infection reduces autoimmune disease symptoms through regulation of inflammatory responses based on hygiene theory. However, the underlying mechanisms remain unclear. BALB/c mice were infected with microcysts of E. granulosus sensu stricto and drank water containing 3.5% dextran sodium sulfate (DSS) at the 100th day post-infection. After 7 days of drinking DSS, the mouse body weight change and disease activity index (DAI) were recorded every day, and colon length and histological score were evaluated after sacrifice. After injection with antigen B (AgB), inducible nitric oxide synthase (iNOS) and Fizz1 expression and F4/80+CD11c+ M1 and F4/80+CD206+ M2 in the peritoneal cells and colon tissues were analysed by qPCR and flow cytometry, respectively. Gut microbiota were profiled by 16S rRNA sequencing of the mouse faec ....

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