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Giving Immunotherapy Cells Resilience to Pass the 'Stress Test' - Vimarsana News

Giving Immunotherapy Cells Resilience to Pass the 'Stress Test'

T cells used in immunotherapy treatments can get exhausted and shut down by fighting cancer cells and tumors. Using a CRISPR-based edit on these cells’ genomes, researchers at UCSF and Gladstone Institutes have rendered the therapeutic cells more resilient against tumors.

Source: ucsf.edu
Scientists discover how to prevent T cell exhaustion to maintain the fight against cancer - Vimarsana News

Scientists discover how to prevent T cell exhaustion to maintain the fight against cancer

When faced with a formidable foe for months on end, the immune system's T cells begin to tire. Whether fighting a cancer or a chronic infection, they become less effective over time, a phenomenon dubbed "T cell exhaustion" by scientists.