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Using next-gen CRISPR tool, Gladstone scienti - Vimarsana News

Using next-gen CRISPR tool, Gladstone scienti

<p>In a study of historic scale, scientists at Gladstone Institutes have created an intricate map of how the immune system functions, examining the detailed molecular structures governing human T cells using the next-generation CRISPR tool known as base editing.&nbsp;Their findings, published in <em>Nature</em>, uncover detailed information that could help overcome the limitations of today&rsquo;s immunotherapies and identify new drug targets for a wide range of diseases, including autoimmune diseases and cancer.&nbsp;</p>

Lego-Like Gene Editing Tool Lets Researchers Improve Cancer Immunotherapy - Vimarsana News

Lego-Like Gene Editing Tool Lets Researchers Improve Cancer Immunotherapy

Scientists used a new method to screen 10,000 combinations of gene edits in immune cells engineered to fight cancer

Lego-Like Gene Editing Tool Lets Researchers Improve Cancer Immunotherapy - Vimarsana News

Lego-Like Gene Editing Tool Lets Researchers Improve Cancer Immunotherapy

/PRNewswire/ -- In recent years, scientists have used gene modification technologies to reprogram immune cells into therapeutics that can attack cancers. But...

Giving Immunotherapy Cells Resilience to Pass the 'Stress Test' - Vimarsana News

Giving Immunotherapy Cells Resilience to Pass the 'Stress Test'

T cells used in immunotherapy treatments can get exhausted and shut down by fighting cancer cells and tumors. Using a CRISPR-based edit on these cells’ genomes, researchers at UCSF and Gladstone Institutes have rendered the therapeutic cells more resilient against tumors.

Source: ucsf.edu