Page 3 - Lab Chip News Today : Breaking News, Live Updates & Top Stories | Vimarsana
Stay updated with breaking news from Lab chip. Get real-time updates on events, politics, business, and more. Visit us for reliable news and exclusive interviews.
Top News In Lab Chip Today - Breaking & Trending Today
Translation regulation is critical for early mammalian embryonic development1. However, previous studies had been restricted to bulk measurements2, precluding precise determination of translation regulation including allele-specific analyses. Here, to address this challenge, we developed a novel microfluidic isotachophoresis (ITP) approach, named RIBOsome profiling via ITP (Ribo-ITP), and characterized translation in single oocytes and embryos during early mouse development. We identified differential translation efficiency as a key mechanism regulating genes involved in centrosome organization and N6-methyladenosine modification of RNAs. Our high-coverage measurements enabled, to our knowledge, the first analysis of allele-specific ribosome engagement in early development. These led to the discovery of stage-specific differential engagement of zygotic RNAs with ribosomes and reduced translation efficiency of transcripts exhibiting allele-biased expression. By integrating our measureme ....
NASA Spaceline Current Awareness List #1,054 16 June 2023 (Space Life Science Research Results) spaceref.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from spaceref.com Daily Mail and Mail on Sunday newspapers.
Monitoring Cytokine Storms in Real Time genengnews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from genengnews.com Daily Mail and Mail on Sunday newspapers.