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Intravenous Vitamin C for Patients Hospitalized With COVID-19

Two randomized clinical trials were harmonized to compare the effect of vitamin C vs control on outcomes in hospitalized patients with COVID-19 who were critica ....

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Newborns are dying because antibiotics are losing their effectiveness

214,000 newborns, primarily in low- and middle-income countries (LMICs0, succumb to sepsis annually due to antibiotic resistance. ....

South Africa , Cape Town , Western Cape , Oneal Russell , Surbhi Malhotra Kumar , Sithembiso Valephi , Manica Balasegaram , Chris Hani Baragwanath , University Of Antwerp , Global Antibiotic Research , University Of London , Child Health Research , Development Partnership , Laboratory Of Medical Microbiology , World Health Organization , Health Research , Medical Research Council Clinical Trials Unit , University College London , Executive Director , Chris Hani Baragwanath Academic Hospital , Neosep Severity Score , Neosep Recovery Score , Principal Investigator , Medical Microbiology ,

Global study highlights deaths from neonatal

The study, conducted from 2018 to 2020, found there was high mortality among infants with culture-positive sepsis (almost 1 in 5 across the hospital sites), and a significant burden of antibiotic resistance. ....

South Africa , Northern Cape , Cape Town , Western Cape , Republic Of , United States , Alessandra Nardone , Manica Balasegaram , Oneal Russell , Surbhi Malhotra Kumar , Sithembiso Velaphi , Chris Hani Baragwanath , University College London , Global Antibiotic Research , World Health Organization As , Development Partnership , Research Council Clinical Trials Unit , Child Health Research , Laboratory Of Medical Microbiology , University Of London , Method Of Research , University Of Antwerp , Medical Research Council Clinical Trials Unit , Executive Director , Chris Hani Baragwanath Academic Hospital , World Health Organization ,

Patterns of antibiotic use, pathogens, and prediction of mortality in hospitalized neonates and young infants with sepsis: A global neonatal sepsis observational cohort study (NeoOBS)

James Neal Russell and colleagues report a global neonatal sepsis observational cohort study (NeoOBS) exploring patterns of antibiotic use, pathogens and prediction of mortality in hospitalised neonates and young infants with sepsis. ....

United Kingdom , United States , Principality Of Monaco , Research Ethics Committee , World Health Organization , Global Antimicrobial Resistance Innovation Fund , Indian Council For Medical Research , German Federal Ministry Of Education , Leo Model Foundation , Sustainable Development Goal , Development Partnership , Melinda Gates Foundation , University Of Antwerp , Laboratory Standard Institute , United Kingdom Department For International Development , Laboratory Of Medical Microbiology , Netherlands Ministry Of Health , United Kingdom Medical Research Council , Luxembourg Ministry Of Development Cooperation , Swiss Federal Office Of Public Health , Luxembourg Ministry Of Health , German Federal Ministry Of Health , Japanese Ministry Of Health , University Of London , United Kingdom Department Of Health , Global Antibiotic Research ,

Global study provides high-quality data to improve treatment of newborn babies with sepsis

A global observational study, which involved more than 3,200 newborn babies suffering from sepsis in 19 hospitals in 11 countries, has shown that many newborns are dying because the antibiotics used to treat sepsis are losing their effectiveness. ....

South Africa , Republic Of , Cape Town , Western Cape , United States , Northern Cape , Alessandra Nardone , Sithembiso Velaphi , Surbhi Malhotra Kumar , Oneal Russell , Danielle Ellis , Manica Balasegaram , Chris Hani Baragwanath , Development Partnership , Global Antibiotic Research , World Health Organization As , University Of London , University Of Antwerp , Laboratory Of Medical Microbiology , Head Of The Laboratory Medical Microbiology , Child Health Research , Health Research , Medical Research Council Clinical Trials Unit , University College London , Latin America , Principal Investigator ,