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Novel Genetic Priority Score Unveiled to Enhance Target Prioritization in Drug Development

Driven by the need for a better way to prioritize targets for drug development, the Icahn School of Medicine at Mount Sinai has led the development of a novel ....

North Yorkshire , United Kingdom , New York , United States , East Harlem , France General , Marie Verbanck , Ghislain Rocheleau , Iains Forrest , Avner Schlessinger , Ben Omega Petrazzini , Davidn Cooper , Carla Ma , Matthew Mort , Novo Nordisk , Postdoctoral Research Award , Merck Co , National Heart , Helmsley Foundation Award , National Institute , Phd Cardiff University , Association Of American Medical Colleges , Mount Sinai Health System , Icahn School Of Medicine At Mount Sinai , National Institutes Of Health , Blood Institute ,

"Genetic priority score" promises to revolutionize drug development

Driven by the need for a better way to prioritize targets for drug development, the Icahn School of Medicine at Mount Sinai has led the development of a novel "genetic priority score" (GPS) that will integrate various types of human genetic data into a single easy-to-interpret score. ....

United Kingdom , North Yorkshire , France General , Iains Forrest , Matthew Mort , Avner Schlessinger , Marie Verbanck , Carla Ma , Davidn Cooper , Ben Omega Petrazzini , Ghislain Rocheleau , Charles Bronfman Institute For Personalized Medicine , Mount Sinai Health System , Phd Cardiff University , National Heart , Icahn School Of Medicine At Mount Sinai , National Institute , Helmsley Foundation Award , French National Research Agency , Blood Institute , Postdoctoral Research Award , Leducq Foundation , Sinai Health , Icahn School , Mount Sinai , Nature Genetics ,

Unlocking the human genome: Innovative machine learning tool predicts functional consequences of genetic variants

Unlocking the human genome: Innovative machine learning tool predicts functional consequences of genetic variants
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David Stein , Avner Schlessinger , National Institutes Of Health , Leducq Foundation , Helmsley Foundation , Charles Bronfman Institute For Personalized Medicine , Genomic Sciences , Mount Sinai Center , Professor Of Pharmacological Sciences , Yuval Itan , Associate Professor , Charles Bronfman Institute , Personalized Medicine , Icahn Mount , Human Gene Mutation Database , Pharmacological Sciences , Associate Director , National Institutes ,

Machine Learning Tool Predicts Effects of Genetic Variants

Machine Learning Tool Predicts Effects of Genetic Variants
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New York , United States , Peterd Stenson , Davidn Cooper , Avner Schlessinger , Sevim Bayrak , David Stein , Yiming Wu , Professor Of Pharmacological Sciences , National Institutes Of Health , Leducq Foundation , China West Normal University , Mount Sinai Center , Helmsley Foundation , Cardiff University , Charles Bronfman Institute For Personalized Medicine , Genomic Sciences , Icahn School Of Medicine At Mount Sinai , Icahn School , Mount Sinai , Genome Medicine , Yuval Itan , Associate Professor , Charles Bronfman Institute , Personalized Medicine , Icahn Mount ,

Inflammation predicts events more than cholesterol in high-risk statin-intolerant patients

Inflammation predicts events more than cholesterol in high-risk statin-intolerant patients
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France General , United States , Eli Lilly , Howard Weintraub , Agepha Pharma , Paulm Ridker , Bitteroot Bio , Leonh Charney Division Of Cardiology , Montai Health , Novo Nordisk , Boehringer Ingelheim , Leducq Foundation , Department Of Medicine , Grossman School Of Medicine , Harvard Medical School , Health Outlook , Peter Munk Advisory Board University Of Toronto , American Heart Association Scientific Sessions , Baim Institute , American Heart Association Scientific , Esperion Therapeutics , Cardiovascular Disease Prevention , Eugene Braunwald Professor , Cardio Therapeutics , Civi Biopharm , Horizon Therapeutics ,