It was Mayo brothers vs. Captain Marvel in 1941 comics
Columnist Tom Weber says parents were looking for upstanding role models for children and the doctors Mayo seemed like the perfect prescription.
Source: postbulletin.com
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A Comic About the Real Life Origin of the Inspiration for Bruce Wayne
Anthony Wayne is remembered for reasons other than his place in American history: his name is the inspiration for the name Bruce Wayne.
Source: bleedingcool.com