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Ligand Pharma Turns To Profit In Q1

Ligand Pharma Turns To Profit In Q1
WASHINGTON (dpa-AFX) - Ligand Pharmaceuticals Inc. (LGND) reported that its net income for the first quarter of 2021 was $18.1 million or $1.05 per share, compared to net loss of $24.1 million, or $1.46 per share, for the same period in 2020.
Net income for the first quarter of 2021 included a $9.1 million net non-cash gain from the value of Ligand s short-term investments, while net loss for the first quarter of 2020 included a $29.7 million net non-cash loss from the value of Ligand s short-term investments.
Adjusted net income for the first quarter was $24.3 million or $1.41 per share, compared to $15.3 million, or $0.89 per share in the prior year. ....

United States , Ligand Pharmaceuticals Inc , ஒன்றுபட்டது மாநிலங்களில் ,

Philogen S.p.A.: Philogen Announces Publication of Best-in-Class FAP-Targeting Small Molecule Ligand (OncoFAP) in PNAS

Philogen S.p.A.: Philogen Announces Publication of Best-in-Class FAP-Targeting Small Molecule Ligand (OncoFAP) in PNAS
(i) Study shows impressive tumor uptake of OncoFAP with unprecedented selectivity against healthy organs - (ii) OncoFAP-based molecules are currently being developed for the imaging and therapy of cancer
SIENA, ITALY / ACCESSWIRE / April 12, 2021 / Philogen S.p.A., a listed clinical-stage biotechnology company focused on the development of innovative medicines based on tumor targeting antibodies and small molecule ligands, is pleased to announce a publication describing the development and the
in vivo characterization of OncoFAP, a best-in-class FAP-targeting small molecule for applications in cancer and inflammation. The paper entitled An Ultra-High Affinity Small Organic Ligand of Fibroblast Activation Protein for Tumor Targeting Applications was published in the peer-reviewed journal ....

Christian Lizak , Dario Neri , Emanuele Puca , Italian Stock Exchange , Business Development , Ultra High Affinity Small Organic Ligand , Fibroblast Activation Protein , Tumor Targeting , Activation Protein , Chief Executive Officer , Italian Stock , Investor Relations , டாரியோ நெறி , இத்தாலிய ஸ்டாக் பரிமாற்றம் , வணிக வளர்ச்சி , ஃபைப்ரோபிளாஸ்ட் செயல்படுத்தல் ப்ரோடீந் , தலைமை நிர்வாகி அதிகாரி , இத்தாலிய ஸ்டாக் , முதலீட்டாளர் உறவுகள் ,

Discovery of cryptic pocket in SARS-CoV-2 may lead to pan-coronavirus therapies

Discovery of cryptic pocket in SARS-CoV-2 may lead to pan-coronavirus therapies
Coronaviruses have been around for a long time and have caused several recent deadly outbreaks. The most recent is the ongoing pandemic of coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
A new research paper published in the
Biophysical Journal describes a novel binding pocket used by a viral non-structural protein (nsp) to form an activated complex with its partner nsp. In so doing, it may have revealed a common target that may be useful in the development of a broad-spectrum antiviral drug against all coronaviruses. ....

Liji Thomas , Biophysical Journal , Corona Virus , Sars Cov 2 , Antiviral Drug , Coronavirus Disease Covid 19 , Protein Synthesis , Ribonucleic Acid , Severe Acute Respiratory , Severe Acute Respiratory Syndrome , Structural Protein , உயிர் இயற்பியல் இதழ் , கொரோனா வைரஸ் , சர்வதேச பரவல் , ப்ரோடீந் தொகுப்பு , கடுமையானது எடுப்போசை சுவாச , கடுமையானது எடுப்போசை சுவாச நோய்க்குறி , கட்டமைப்பு ப்ரோடீந் ,

Study targets main protease of SARS-CoV-2 involved in viral replication

The main protease of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an enzyme implicated in the transcription and replication of the coronavirus. New research led by S. Samar Hasnain from the University of Liverpool in the United Kingdom used the selenium-containing drug Ebselen to analyze the SARS-CoV-2 main protease (Mpro). ....

United Kingdom , Jocelyn Solis Moreiramar , Jocelyn Solis Moreira , University Of Liverpool , Coronavirus Disease Covid 19 , Sars Cov 2 , Corona Virus , Severe Acute Respiratory , Severe Acute Respiratory Syndrome , ஒன்றுபட்டது கிஂக்டம் , ஜாஸ்லைந் ஸோலிஸ் மோர்ர , பல்கலைக்கழகம் ஆஃப் லிவர்பூல் , கொரோனா வைரஸ் , எதிர் மின்னணு , கடுமையானது எடுப்போசை சுவாச , கடுமையானது எடுப்போசை சுவாச நோய்க்குறி ,

Narrowing down on small molecular inhibitors of SARS-CoV-2 key protease

Narrowing down on small molecular inhibitors of SARS-CoV-2 key protease
A recent methodological study by researchers from the University of Luxembourg shows that the combination of virtual screening approaches, molecular dynamics simulations and machine learning can substantially facilitate small molecule screening investigations targeted at key SARS-CoV-2 viral proteins. Their findings are currently available on the
bioRxiv preprint server.
The coronavirus disease 2019 (COVID-19) pandemic, which is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is still a major challenge for healthcare systems and economies worldwide. And while vaccines are being rolled out all over the world, the available drug-based therapies are still lacking. ....

Ganesh Babu Manoharan , Daniel Abankwa , Enrico Glaab , University Of Luxembourg , Coronavirus Disease Covid 19 , Sars Cov 2 , Corona Virus , Health Care , In Vitro , Machine Learning , Severe Acute Respiratory , Severe Acute Respiratory Syndrome , கணேஷ் பாபு மனோஹரன் , பல்கலைக்கழகம் ஆஃப் லக்ஸம்பர்க் , கொரோனா வைரஸ் , ஆரோக்கியம் பராமரிப்பு , இல் விட்ரோ , இயந்திரம் கற்றல் , சர்வதேச பரவல் , கடுமையானது எடுப்போசை சுவாச , கடுமையானது எடுப்போசை சுவாச நோய்க்குறி ,