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Father's Sperm Changes Linked to Autism Traits in Children

Father's Sperm Changes Linked to Autism Traits in Children
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A Mother's Blood May Carry the Secret to One Type of Autism

Maternal autoantibody–related autism spectrum disorder (MAR ASD) is marked by specific maternal antibodies that react to certain proteins in the fetal brain. Examining the plasma of expecting mothers, researchers found mothers with reactivity to one of the nine MAR ASD patterns were eight times as likely to have a child diagnosed with autism.

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Antidepressants safe during pregnancy

Antidepressants safe during pregnancy
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Covid-19 gave scientists a way to study how brain disorders arise


By Sara Reardon April 26, 2021Reprints
A mutation in an autism-related gene is shown. By studying Covid-19 patients, psychiatrists hope to gain new insights about how disorders like schizophrenia and autism arise, as well as why people with these conditions tend to suffer worse effects from viral infection.
National Institute of Neurological Disorders and Stroke, NIH
While the Covid-19 pandemic put many human research studies on hold, neuroscientist Grainne McAlonan of Kings College London saw it as a fortuitous opportunity — a chance to accelerate her search for early signs of neurodevelopmental disorders in fetuses and newborns.
McAlonan knew that if a mother is infected by a virus during pregnancy, her child has a slightly greater chance of developing such disorders, including autism, although the overall risk is very low. The novel coronavirus gave her a way to study how viral infection and the immune response affect the developing brain, and why a small number of infants are susceptible to neurological changes while the vast majority are not. By imaging the brains of babies who were exposed to Covid-19 while in utero, McAlonan plans to compare their development patterns and perhaps find similarities and additional risk factors among the infants who later develop mental disorders.

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