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Overdosing on chemo: A common gene test could save hundreds of lives each year

Overdosing on chemo: A common gene test could save hundreds of lives each year
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Chemo toxicity: A common gene test could save hundreds of lives each year

Chemo toxicity: A common gene test could save hundreds of lives each year
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Overdosing on Chemo: A Common Gene Test Could Save Hundreds of Lives Each Year

Patients with variants in the DPYD gene have an increased risk of severe toxicity and death from fluoropyrimidine chemotherapy, but many US cancer patients are not being tested for DPYD variants. Fluoropyrimidine chemotherapy kills more than 275,000 US cancer patients each year, but routine genetic testing could change that. ....

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A quick test could protect against fatal chemo overdose, yet few cancer doctors use it

A quick test could protect against fatal chemo overdose, yet few cancer doctors use it
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A quick, cheap test could protect against fatal chemo overdose. Why do cancer doctors resist it?

The chemotherapy drug 5-FU can be toxic to some people with cancer. A quick, cheap test can show if chemo is safe for a patient, but few doctors order it. ....

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