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Escape from oblivion: How the brain reboots after deep anesthesia

Credit: Jacob Dwyer, Michigan Medicine
Millions of surgical procedures performed each year would not be possible without the aid of general anesthesia, the miraculous medical ability to turn off consciousness in a reversible and controllable way.
Researchers are using this powerful tool to better understand how the brain reconstitutes consciousness and cognition after disruptions caused by sleep, medical procedures requiring anesthesia, and neurological dysfunctions such as coma.
In a new study published in the journal
eLife, a team led by anesthesiologists George Mashour, M.D., Ph.D. of University of Michigan Medical School, Michigan Medicine, Max Kelz, M.D., Ph.D. of the University of Pennsylvania Medical School, and Michael Avidan, MBBCh of the Washington University School of Medicine used the anesthetics propofol and isoflurane in humans to study the patterns of reemerging consciousness and cognitive function after anesthesia. ....

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Study: Don't count on caffeine to fight sleep deprivation

Sleep scientists assessed how effective caffeine was in counteracting the negative effects of sleep deprivation on cognition. ....

United States , Kimberly Fenn , Michigan State University , Michigan State , Learning Lab , Experimental Psychology , State University , Circadian Rhythm , Leep Sleep Disorders , Social Behavioral Science , Mental Health , Decision Making Problem Solving , Memory Cognitive Processes , Perception Awareness , ஒன்றுபட்டது மாநிலங்களில் , கிம்‌பர்லீ ஃபெந் , மிச்சிகன் நிலை பல்கலைக்கழகம் , மிச்சிகன் நிலை , கற்றல் ஆய்வகம் , சோதனை உளவியல் , நிலை பல்கலைக்கழகம் ,

Intermittent fasting in mice effective at promoting long term memory retention

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A new study from the Institute of Psychiatry, Psychology and Neuroscience (IoPPN) at King s College London has established that Intermittent Fasting (IF) is an effective means of improving long term memory retention and generating new adult hippocampal neurons in mice, in what the researchers hope has the potential to slow the advance of cognitive decline in older people.
The study, published today in
Molecular Biology, found that a calorie restricted diet via every other day fasting was an effective means of promoting Klotho gene expression in mice. Klotho, which is often referred to as the longevity gene has now been shown in this study to play a central role in the production of hippocampal adult-born new neurons or neurogenesis. ....

United Kingdom , City Of , Makoto Kuro , Gisele Pereira Dias , Lindseyj Aimone , Patrick Obrien , Jamesb Aimone , Tytus Murphy , Selda Ahmet , Doris Stangl , Benjamin Morisse , Sandrine Thuret , King Io , King College London , Initiative In Brain Health , Psychiatry Research , Institute Of Psychiatry , Research Council United Kingdom , Qs World University Rankings , College London , Intermittent Fasting , Molecular Biology , Calorie Restricted , Medical Research Council , Psychiatry Research Trust , Allen Initiative ,

Supersensitive connection causes hatred of noises

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A supersensitised brain connection has been identified in people who suffer from misophonia, an extreme reaction to trigger sounds.
For the first time, researchers led by Newcastle University, have discovered increased connectivity in the brain between the auditory cortex and the motor control areas related to the face, mouth and throat.
Publishing today, in the
Journal of Neuroscience, lead author Dr Sukhbinder Kumar, Newcastle University Research Fellow in the Biosciences Institute said: Our findings indicate that for people with misophonia there is abnormal communication between the auditory and motor brain regions - you could describe it as a supersensitised connection . ....

Timothyd Griffiths , Tim Griffiths , Phillipe Gander , Pradeep Dheerendra , William Sedley , Sukhbinder Kumar , Ester Benzaqu , Mercede Erfanian , Dorise Bamiou , Newcastle University , Professor Of Cognitive Neurology At Newcastle University , Newcastle University Research , Biosciences Institute , Newcastle University Research Fellow , Cognitive Neurology , Meher Lad , Medicine Health , Hearing Speech , Coping Phobias , Memory Cognitive Processes , Perception Awareness , நேரம் கிரிஃபித்ஸ் , சுக்பிந்தர் குமார் , நியூகேஸில் பல்கலைக்கழகம் , உயிர் அறிவியல் நிறுவனம் , நியூகேஸில் பல்கலைக்கழகம் ஆராய்ச்சி சக ,

The brain learns faces fastest in person

The neural representation of a familiar face strengthens faster when you see someone in person, according to a new study published in JNeurosci. ....

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