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Fentanyl can induce changes similar to autism-like behaviors in young mice

Fentanyl, a mu-opioid receptor agonist, is one of the most commonly used analgesics in the hospital and may induce long-lasting behavioral and somatosensory impairment in rodents. ....

United Kingdom , United States , Chun Cheng , Zhongcong Xie , Mengzhu Li , Emily Henderson , Zhihao Sheng , Jed Barash , Qidong Liu , W Andrew Kofke , National Natural Science Foundation Of China , Department Of Anesthesia , Science Research , University Of Pennsylvania , Technology Of China , Ministry Of Science , Massachusetts General Hospital , British Journal , Basic Science Research , Critical Care , Pain Medicine , Harvard Medical , Shanghai First Maternity , Infant Hospital , National Natural Science Foundation , Medical School ,

Fentanyl May Cause Autism-Like Behavior in Young Mice

Exposure to the opioid fentanyl induces autism-like behaviors in mice by activating mu-opioid receptors in the anterior cingulate cortex. ....

United Kingdom , United States , Chun Cheng , Michael Morrison , Zhongcong Xie , Mengzhu Li , Zhihao Sheng , Jed Barash , Qidong Liu , W Andrew Kofke , Department Of Anesthesia , Science Research , University Of Pennsylvania , Massachusetts General Hospital , British Journal , Yuan Shen , Basic Science Research , Critical Care , Pain Medicine , Harvard Medical , Shanghai First Maternity , Infant Hospital , Neuroscience Newsletter ,