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Fentanyl, a mu-opioid receptor agonist, is one of the most commonly used analgesics in the hospital and may induce long-lasting behavioral and somatosensory impairment in rodents.
Exposure to the opioid fentanyl induces autism-like behaviors in mice by activating mu-opioid receptors in the anterior cingulate cortex.
1 Governance professor Beth Simone Noveck, who formerly served as the first White House deputy chief technology officer, believes that “public entrepreneurship” can counter the failures that have dominated public policy design in the United States since the 1960s. Her new book, Solving Public Problems, revisits the four stages of policy design—identifying problems, identifying solutions, designing for implementation, and evaluation and evolution—while identifying 20 crucial decisions that prioritize “human-centered public policies.” Experts often expend much effort on program des...