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License and Commercialization agreement between Pierre Fabre and ValenzaBio on an anti-IGF-1R antibody for the development of a novel treatment in Thyroid Eye Disease (TED)


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BESTHESDA, Maryland and CASTRES, France, April 8, 2021 /PRNewswire/ The US biopharmaceutical company ValenzaBio and the French pharmaceutical group Pierre Fabre announced today the signing of a license agreement of a preclinical insulin-like growth factor-1 receptor (IGF-1R) antagonist antibody, for the treatment of Thyroid Eye Disease (TED), an endocrine disease with unmet medical need. ValenzaBio received from Pierre Fabre the worldwide and exclusive rights to develop and commercialize, outside of oncology, the anti-IGF-1R antibody, discovered by Pierre Fabre at its Center of immunology located in Saint-Julien-en-Genevois (France), with the aim of treating patients suffering from TED. Other indications in rare diseases could also be developed by ValenzaBio. In parallel, Pierre Fabre is pursuing the development of its anti-IGF-1R ADC program (W0101) in oncology. ....

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France's Macron announces end of elite ENA college


France s Macron announces end of elite ENA college
Updated:
Updated:
April 09, 2021 04:02 IST
The Ecole Nationale d Administration, known as ENA, is today a small Strasbourg-based finishing school for top civil servants that has become a symbol of elitism in France.
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French President Emmanuel Macron   | Photo Credit:
AP
The Ecole Nationale d Administration, known as ENA, is today a small Strasbourg-based finishing school for top civil servants that has become a symbol of elitism in France.
French President Emmanuel Macron announced Thursday plans to scrap France s elite ENA graduate school, which four modern presidents have attended including him, and replace it with a new institute. ....

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Christie's Paris announces Impressionist & Modern Art & Works on Paper sale


Christie s Paris announces Impressionist & Modern Art & Works on Paper sale
Edgar Degas, Danseuse en maillot, au repos, 1881-83. Charcoal and estompe on paper, 30 ¼ x 43 ½ in. Estimate: €300,000 - 500,000. © Christie s Images Ltd 2021.
PARIS
.- The highly anticipated event next month in Christie s Paris Impressionist & Modern Art department is the upcoming sale to be held on Wednesday 14 April 2021. Comprising around 170 lots, the sale will begin with a section of Modern Works on Paper, which will be immediately followed by a section dedicated to Impressionist and Modern paintings and sculptures. Prices range from €700 to €500,000 and the overall low estimate is close to €8.5m. The sale will be led by a rare watercolour by Robert Delaunay, Manège de cochons, embodying the Orphism advocated by the latter, and will bring together the major figures of the late 19th and early 20th centuries. Three prestigious private collections are at the heart of the two section ....

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The Letter n°930 - Robert Schuman Foundation


The Letter n°930
Eric Maurice
While the European democratic system is subject to hybrid threats from outside, it is being challenged from within by the current governments in Hungary and Poland and their systemic undermining of checks and balances and guarantees of political alternation. Independent judges and an unfettered press remain the last two bulwarks against power grabs and authoritarian temptations. For the European Union, it is essential to act as a priority to preserve these checks and balances.
Prime Minister Boïko Borissov s Citizens for the European Development of Bulgaria (GERB) party, which ran in coalition with the Union of Democratic Forces (SDS), came first in the Bulgarian parliamentary elections of 4 April, with 26.14% of the vote. Such a People Exist, a populist party created by singer and TV presenter Slavi Trifonov, came second with 17.73%, ahead of the Socialist Party (15.02%) which lost its status as the first opposition party. Boyk ....

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