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Author summary Why was this study done? Compared to Alzheimer’s disease (AD), dementia with Lewy bodies (DLBs) is associated with accelerated cognitive decline, lower quality of life, higher caregiver burden, shorter lifespan, and higher costs of care, as well as increased rates of admission to general hospitals and residential care and longer length of stay. Although there are no disease-modifying medications for DLB, there is evidence suggesting that acetylcholinesterase inhibitors (AChEIs) and glutamate N-methyl-D-aspartate receptor antagonists (specifically, memantine) are efficaci...

Author summary Why was this study done? Compared to Alzheimer’s disease (AD), dementia with Lewy bodies (DLBs) is associated with accelerated cognitive decline, lower quality of life, higher caregiver burden, shorter lifespan, and higher costs of care, as well as increased rates of admission to general hospitals and residential care and longer length of stay. Although there are no disease-modifying medications for DLB, there is evidence suggesting that acetylcholinesterase inhibitors (AChEIs) and glutamate N-methyl-D-aspartate receptor antagonists (specifically, memantine) are efficaci...

In low- and middle-income countries, poverty and impaired growth prevent children from meeting their cognitive developmental potential. There are few studies investigating these relationships in high-income settings. Participants were 12,536 children born between 2000 and 2002 in the UK and participating in the Millennium Cohort Study (MCS). Short stature was defined as having a height-for-age 2 or more standard deviations below the median (≤ − 2 SDS) at age 3 years. Standardized British Abilities Scales II (BAS II) language measures, used to assess language de...

To update and internally validate a model to predict children and young people (CYP) most likely to experience long COVID (i.e. at least one impairing symptom) 3 months after SARS-CoV-2 PCR testing and to determine whether the impact of predictors differed by SARS-CoV-2 status. Data from a nationally matched cohort of SARS-CoV-2 test-positive and test-negative CYP aged 11–17 years was used. The main outcome measure, long COVID, was defined as one or more impairing symptoms 3 months after PCR testing. Potential pre-specified predictors included SARS-CoV-2 status, sex, age, ethnicity, depr...

The Office for National Statistics’ survey exposed divisions across the country in terms of how people are being affected by higher living costs.