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Multiple COVID-19 variants of concern have reached Houston, Texas

Multiple COVID-19 variants of concern have reached Houston, Texas
New research by a team at Houston Methodist Hospital in the United States has modeled the aggressive genomic sequencing of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) observed in the United Kingdom to document viral community spread in Houston, Texas.
Houston has thus become the first American city to document four SARS-CoV-2 variants of concern.
Here we report discovery of the UK (B.1.1.7), South Africa (B.1.351), and Brazil (P.1) SARS-CoV-2 variants of concern from patients in the Houston metropolitan region. We also identified geographically-widespread dissemination of the Cal.20C California (B.1.429 and B.1.427) variants of interest. These four SARS-CoV-2 variants are distributed across a large geospatial region in the metropolitan region, indicating successful patient-to-patient transmission among Houstonians.” ....

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Houston Methodist finds multiple cases of significant coronavirus mutations, including Brazil strain

Houston Methodist finds multiple cases of significant coronavirus mutations, including Brazil strain
Infectious disease pathologists have sequenced more than 20,000 genomes of SARS-CoV-2 virus
Newswise HOUSTON-(March 2, 2021) – Houston Methodist discovered 28 cases of coronavirus variants in its latest batches of virus genomes sequenced from patients with positive COVID-19 tests, including what might be the state’s first confirmation of four cases of the Brazil variant known as P.1. Houston is the first city in the U.S. to have all the major variants documented by genome sequencing.
“There is evidence to indicate that the Brazil P.1 variant may spread faster and be resistant to certain vaccines and monoclonal antibody therapies – much like the South Africa variant known as B.1.351 – and may still be able to cause disease in some people who are inoculated with Pfizer or Moderna vaccines,” said James M. Musser, M.D., Ph.D., chair of the Department of Pathol ....

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