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Link between aldehydes and premature aging revealed

A team of researchers at Nagoya University in Japan has discovered that aldehydes are metabolic byproducts associated with premature aging.

Nagoya , Aichi , Japan , Mayuko-shimada , Yuka-nakazawa , Yasuyoshi-oka , Nagoya-university , Tomoo-ogi-of-nagoya-university , Nature-cell-biology , Tomoo-ogi , Aging

DNA repair process key to memory formation, study finds

Study reveals that learning triggers a series of molecular events including DNA damage and repair in hippocampal neurons, mediated by TLR9, crucial for memory formation.

Billion-photos , Cornu-ammonis , Dna , Denosine , Amp , Ell , Reb , Na-damage , Ene , Ene-expression , Ippocampus

Study reveals e-cigarette users with limited smoking history show similar DNA alterations as smokers

A study assessed the effect of tobacco smoking and electronic cigarette (e-cigarettes) use on DNA methylation changes associated with carcinogenesis.

Popov-shutterstock , Cancer-research , Cigarette , Na , Moking , Iomarker , Lood , Ancer , Arcinogenesis , Ell , Na-damage

MUTYH gene mutation linked to increased risk of various solid tumors

A gene associated with colorectal cancer appears to also play a role in the development of other solid tumors, according to a study of over 350,000 patient biopsy samples conducted by researchers at the Johns Hopkins Kimmel Cancer Center, the Johns Hopkins Bloomberg School of Public Health and Foundation Medicine.

Massachusetts , United-states , United-kingdom , Emmanuel-antonarakis , Channing-paller , Johns-hopkins , Alexandra-maertens , University-of-minnesota-masonic-cancer-center , Johns-hopkins-kimmel-cancer-center , Johns-hopkins-university-school-of-medicine , University-of-minnesota-medical-school , Research-programs

Study reveals unexpected link between cell membrane damage and cellular senescence

Our cells are surrounded by a fragile membrane that's only 5 nanometers thick, 1/20 of a soap bubble. Cells are easily damaged by physiological activities, including muscle contraction and tissue injury.

Nurhanani-razali , Keiko-kono , Kojiro-suda , Yohsuke-moriyama , Okinawa-institute-of-science , Professor-keiko-kono , Aging , Ell , Alcium , Ancer , Ell-division , Ell-membrane

Magnesium's pivotal role in slowing aging's impact

Review highlights magnesium's critical role in mitigating aging hallmarks, including telomere attrition, genomic instability, epigenetic alterations, loss of proteostasis, mitochondrial dysfunction, cellular senescence, and stem cell exhaustion, suggesting that maintaining adequate magnesium levels could support healthy aging.

Image-credit , Aging , Agnesium , Ell , Ell-cycle , Ell-division , Hromatin , Hronic , Ognitive-function , Iabetes , Na

Researchers find new clue to treating aggressive Wilms tumor subtype

An international team, led by researchers at Nagoya University in Japan, may have determined why the diffuse anaplasia (DA) subtype of Wilms tumor (WT) resists chemotherapy.

Japan , Nagoya , Aichi , Kaname-uno , Nagoya-university-graduate-school-of-medicine , Lund-university-joint-degree-program , Nagoya-university , Modern-pathology , Nagoya-university-graduate-school , Lund-university-joint-degree , Chemotherapy , Umor