Can Epigenetic Therapy Overcome Endocrine Resistance in Breast Cancer?
Scientists have uncovered the cause behind the development of endocrine resistance in breast cancer and proposed potential treatment avenues for patients.
Source: medindia.net
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Epigenetic Therapy Reverses Endocrine-Resistant Breast Cancer Growth
Garvan researchers have revealed a reason why endocrine resistance develops in breast cancers and how to potentially treat it in patients.
Source: technologynetworks.com
Study exploits biomolecular condensates to inhibit androgen receptor in prostate cancer
Transcription factors play essential roles in turning the genetic information encoded in genes into proteins in all cells and organisms.
Source: news-medical.net
Hard to drug: Protein droplets reveal new way
<ul> <li>Many of the most potent human oncoproteins belong to a class of proteins called transcription factors, but designing small molecule drugs that target transcription factors is a major challenge.</li> <li>An international team of researchers from the Institute for Research in Biomedicine (IRB Barcelona), the Max Planck Institute for Molecular Genetics (MPIMG), BC Cancer (University of British Columbia) and other institutions has discovered a potential way to target the androgen receptor, the most prominent oncogenic transcription factor in prostate cancer, base...
Source: eurekalert.org
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Source: nature.com