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Patients With NDMM Who Fail QUAD Treatment Within 18 Months Show Poor Response to Subsequent Treatments

The investigators note that patients with newly diagnosed multiple melanoma who receive quadruplet treatment have unmet needs that must be further examined in future research.

United-kingdom , British , Key-takeaways , Newly-diagnosed-multiple-myeloma , Stem-cell-transplantation , Treatment-failure-duration , Progression-free-survival , Future-directions , British-journal ,

The Evolving Treatment Paradigm for Transplant Ineligible MM

The expert panel discusses how the standard of care for transplant-ineligible NDMM has evolved and reviews recent updates in this space.

Multiple-myeloma , Evolving-treatment-paradigm , Transplant-ineligible , Mm , Newly-diagnosed-multiple-myeloma , Ndmm , Mm-treatment , Transplant-eligible , Daratumumab , Lenalidomide , Dexamethasone

Highlights from ASH 2023 in Transplant-Eligible NDMM

Experts in multiple myeloma discuss highlights from the ASH 2023 meeting around transplant-eligible NDMM with particular focus on the PERSEUS and GRIFFIN trials and the clinical implications of the results of these studies.

Multiple-myeloma , Mm , Newly-diagnosed-multiple-myeloma , Ndmm , Mm-treatment , Transplant-eligible , Perseus , Griffin-trial , Perseus-trial , Daratumumab , Lenalidomide

Advances in the Treatment of High-Risk MM

Clinical insights on the definition of high-risk multiple myeloma and the treatment of patients with high risk disease, including how the results from the IsKia trial might impact practice.

Multiple-myeloma , Mm , Newly-diagnosed-multiple-myeloma , Ndmm , Mm-treatment , Transplant-eligible , High-risk , Standard-risk , Iskia , Isatuximab , Carfilzomib

Role of Transplant and MRD in Newly Diagnosed MM

Amrita Krishnan, MD, and Saad Z. Usmani, MD, MBA, FACP, offer their perspectives on the role of stem cell transplant and MRD testing in patients with newly diagnosed multiple myeloma.

Saadz-usmani , Multiple-myeloma , Newly-diagnosed , Mm , Newly-diagnosed-multiple-myeloma , Ndmm , Mm-treatment , Transplant-eligible , High-risk , Standard-risk , Quadruplet

Results of the Phase III Randomized IsKia Trial: Isatuximab-Carfilzomib-Lenalidomide-Dexamethasone Vs Carfilzomib-Lenalidomide-Dexamethasone as Pre-Transplant Induction and Post-Transplant Consolidation in Newly Diagnosed Multiple Myeloma Patients

Francesca Gay, MD, PhD, presents results from the phase III randomized IsKia trial investigating isatuximab-carfilzomib-lenalidomide-dexamethasone as pre-transplant induction and post-transplant consolidation in patients with newly diagnosed multiple myeloma.

California , United-states , San-diego , Iskia-trial , Pre-transplant-induction , Post-transplant-consolidation , Newly-diagnosed-multiple-myeloma , Multiple-myeloma , Iskia , Iskia-study , Isatuximab