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Chemoautotrophic production of gaseous hydrocarbons, bioplastics and osmolytes by a novel Halomonas species | Biotechnology for Biofuels and Bioproducts

Production of relatively low value, bulk commodity chemicals and fuels by microbial species requires a step-change in approach to decrease the capital and operational costs associated with scaled fermentation. The utilisation of the robust and halophilic industrial host organisms of the genus Halomonas could dramatically decrease biomanufacturing costs owing to their ability to grow in seawater, using waste biogenic feedstocks, under non-sterile conditions. We describe the isolation of Halomonas rowanensis, a novel facultative chemoautotrophic species of Halomonas from a natural brine spring. We investigated the ability of this species to produce ectoine, a compound of considerable industrial interest, under heterotrophic conditions. Fixation of radiolabelled NaH14CO3 by H. rowanensis was confirmed in mineral medium supplied with thiosulfate as an energy source. Genome sequencing suggested carbon fixation proceeds via a reductive tricarboxylic acid cycle, and not the Calvin–Bense ....

United Kingdom , East Sussex , United States , Takara Bio , Formedium Norfolk , Pacific Biosciences , Nantwich Cheshire , Dnadist Phylip , Agilent Technologies , Prof Liu University Of Liverpool , Professor Guo Qiang Chen Tsinghua University , New England Biolabs , Prof Liu , Aydingkol Lake , Professor Guo Qiang Chen , Tsinghua University , Old Biot , Greater Manchester , Pacbio Sequel , Fragment Analyzer , Express Template Prep Kit , Pacific Biosciences Sequel , Study Title , Biocyc Pathway Tools , Agilent Hi Plex H , Ultima Gold ,

Frontiers | State of Shark and Ray Genomics in an Era of Extinction

Chondrichthyan species (sharks, rays, skates, and chimaeras) are a class of high ecological, economic, and cultural significance, and yet they are the most threatened taxa in the marine environment. The creation of reference chromosome-length genome assemblies allows for conservation genomics methods, such as population and ecological genomics, to be utilized. Despite being greatly threatened and of great importance in maintaining ecosystem function, chondrichthyan species have been repeatedly absent from conservation-based genome sequencing projects. Less than 1% of these species have a genome sequence, despite their almost 50% either threatened or Data Deficient conservation status. Most notably, there are seven orders within this class without any genome representation. In this review, we identify gaps in chondrichthyan genomic resources and demonstrate how the lack of genomic resources for this major taxonomic class is limiting the conservation of these already difficult to conserv ....

New York , United States , South Africa , Nordrhein Westfalen , City Of , United Kingdom , Eastern Cape , New Zealand , Indian Ocean , South African , Oxford Nanopore , Pacific Ocean , Omarion Taylor , Pacific Biosciences , Pacific Biosciences Pacbio , Van Straalen , Van Herwerden , Jock Clough Marine Foundation , Robertson Research Fellowship , Industrial Research Organisation , Indian Ocean Marine Research Centre , Sensor Technology Ico , Marine Sciences , Department Of Primary Industries , Australian Institute Of Marine Science , Academy Sci ,

UofL researchers lead the call to increase genetic diversity in immunogenomics

UofL researchers lead the call to increase genetic diversity in immunogenomics
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United States , United Kingdom , South Africa , French Polynesia , Saudi Arabia , Oscar Rodriguez , Melissa Smith , Yana Safonova , Coreyt Watson , Corey Watson , University Of Louisville Department Biochemistry , Department Of Biochemistry , University Of Louisville Sequencing Technology Center , Pacific Biosciences Sequel , Louisville Sequencing Technology , Louisville Department , Molecular Genetics , Nature Methods , ஒன்றுபட்டது மாநிலங்களில் , ஒன்றுபட்டது கிஂக்டம் , பிரஞ்சு பாலிநீஷியா , சவுதி அரேபியா , ஆஸ்கார் ரோட்ரிக்ஸ் , மெலிசா ஸ்மித் , யான சாபொநோவ , கோரி வாட்சன் ,

Researchers Lead Call to Increase Genetic Diversity in Immunogenomics

Researchers Lead Call to Increase Genetic Diversity in Immunogenomics
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United States , United Kingdom , South Africa , French Polynesia , Saudi Arabia , Oscar Rodriguez , Melissa Smith , Yana Safonova , Coreyt Watson , Corey Watson , Department Of Biochemistry , University Of Louisville Uofl Department Biochemistry , University Of Louisville Sequencing Technology Center , University Of Louisville , Researchers Lead Call , Increase Genetic Diversity , Pacific Biosciences Sequel , Louisville Sequencing Technology , Molecular Genetics , Nature Methods , ஒன்றுபட்டது மாநிலங்களில் , ஒன்றுபட்டது கிஂக்டம் , பிரஞ்சு பாலிநீஷியா , சவுதி அரேபியா , ஆஸ்கார் ரோட்ரிக்ஸ் , மெலிசா ஸ்மித் ,