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Researchers compared the nasal microbiome of coronavirus disease 2019 (COVID-19) patients, healthy individuals, and healthcare workers. These studies indicated an increase in the pathogen Pseudomonas aeruginosa present in the nasal microbiome of COVID-19 patients, which may be responsible for other secondary infections.

Do mixed COVID-19 vaccines provide immunity? The initial results of the CombivacS trial found that the antibody levels in individuals increased by 150 times when the Pfizer messenger ribonucleic acid (mRNA) vaccine was given after a first dose of the AstraZeneca severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine, with only mild common side effects. Introduction The AstraZeneca coronavirus disease 2019 (COVID-19) vaccine was suspended by several countries in the European Union following reports of blood clots leading to deaths in some people who had previously received the va...

B.1.1.7 not associated with change in serial interval of COVID-19 With data obtained from the Virus Watch study in England and Wales, researchers found that the serial interval of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is broadly similar to estimates from previous studies and there is no evidence that the B.1.1.7 variant is associated with any change. Serial interval is a key parameter in epidemiological studies of infectious diseases. It is an estimation of the spread of the disease and is often measured as the time interval between symptom onset in a primary case and t...

A SARS-CoV-2 vaccine candidate based on B.1.351 spike trimer shows broad neutralizing capability Researchers tested a vaccine candidate in mice with up to three doses and found it produces high levels of antibodies against both SARS-CoV-2 variants of concern and the original virus strain. The emergence of several new mutations of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to concerns about increased transmissibility of the virus and the ability of vaccines to protect against them. Some studies point to lower efficacy of vaccines to the new strains compared to th...

Study reports new monoclonal antibodies with broad neutralizing capabilities against betacoronaviruses (including SARS-CoV-2) The monoclonal antibodies identified target the S2 subunit of the virus spike protein and inhibit viral infection by preventing membrane fusion. Coronaviruses are pathogens found in many birds and mammals like bats, pangolins, and pigs. There have been many instances of these viruses spilling over to humans, indicating they have a broad capability to spread between many distinct species. Apart from the virus causing the current pandemic, the severe acute respiratory s...