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Novel Subcutaneous Biologics Show Promise in AD

Patients with moderate to severe atopic dermatitis could soon have more therapeutic options, with monoclonal antibodies targeting novel immune pathways that reduce disease severity, suggest two trials. ....

United States , Noord Holland , Eric Simpson , Stephan Weidinger , Tiagor Matos , Department Of Dermatology , European Academy Of Dermatology , Kymab Ltd , University Hospital Schleswig Holstein , Amsterdam University Medical Centers , Oregon Health Science University , European Academy , Eczema Area , Severity Index , Oregon Health , Science University , Medscape Medical News , Validated Investigator Global Assessment , Atopic Dermatitis , Body Surface Area , Peak Pruritus Numerical Rating Scale , Biologic Therapy , Monoclonal Antibody , Corneal Disease , Preventive Screening , Severity Indices ,

Tapinarof Effective for AD in Patients as Young as 2 years

Tapinarof cream, 1%, an aryl hydrocarbon receptor agonist, was approved in 2022 for treating plaque psoriasis in adults. ....

United States , Jonathani Silverberg , Eric Simpson , European Academy Of Dermatology , Oregon Health Science University , Mcgovern Medical School , Interdisciplinary Center , Dermavant Sciences , Drug Administration , George Washington University , European Academy , Validated Investigator Global Assessment , Oregon Health , Science University , Peak Pruritus , Numerical Rating Scale , Chronic Pruritus , New England Journal , Atopic Dermatitis , Topical Therapy , Plaque Psoriasis , Skin Lesion , Clinical Research , Clinical Trials , Linical Studies ,

Novel Agent Seladelpar Improves Markers of PBC Activity

For 1 in 4 patients with primary biliary cholangitis (PBC) who received the investigational PPAR-delta agonist, alkaline phosphatase levels normalized. ....

United States , Aleksander Krag , Gideon Hirschfeld , Odense Denmark University Hospital , University Of Southern Denmark , Toronto Center , Liver Disease , Toronto General Hospital , Liver Meeting , American Association , Liver Diseases , Cymabay Therapeutics , North America , South America , Peak Pruritus Numerical Rating Scale , Southern Denmark , University Hospital , Enhanced Liver Fibrosis , Biliary Disease , Allbladder Disease , Liver Enzymes , Liver Studies , Liver Fibrosis , Ipid Management , Low Ldl Cholesterol , Ow Low Density Lipoprotein Cholesterol ,

Prurigo Nodularis Dx Delay in Skin Types Gains Significance

Patients with darker skin types tend to have larger nodules that might vary in shape relative to lighter skin types, according to Shawn Kwatra, MD. ....

New York , United States , Shawng Kwatra , Castle Biosciences , Galderma Incyte , Andrewf Alexis , Johns Hopkins Itch Center , Color Update , Numeric Rating Scale , Dermatology Life Quality Index , New England Journal , Weill Cornell Medicine , Social Determinants Of Health , Prurigo Nodularis , Iological Marker , Osinophil Granulocytes , Biologic Therapy , Genomic Medicine , Edicine Genomic ,

Seladelpar Improves Markers of Cholestasis, Pruritus in Patients with PBC

Phase 3 data presented at The Liver Meeting 2023 from the American Association for the Study of Liver Diseases demonstrated the safety and efficacy of seladelpar in patients with primary biliary cholangitis through 12 months of treatment. ....

Gideon Hirschfield , Terry Horner , Drug Administration , University Of Toronto , Autoimmune Liver Disease Research , Liver Meeting , American Association , Liver Diseases , Terry Horner Chair , Primary Biliary Cholangitis , Phase 3 ,