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Chromatin accessibility is essential in regulating gene expression and cellular identity, and alterations in accessibility have been implicated in driving cancer initiation, progression and metastasis1–4. Although the genetic contributions to oncogenic transitions have been investigated, epigenetic drivers remain less understood. Here we constructed a pan-cancer epigenetic and transcriptomic atlas using single-nucleus chromatin accessibility data (using single-nucleus assay for transposase-accessible chromatin) from 225 samples and matched single-cell or single-nucleus RNA-sequencing exp...

Future Market Insights recently published a study projecting that the Lab Accessories Market demand will grow at a high CAGR of 6.8%, expanding from US$ 585.0 Million in 2022 to US$ 1.1 Billion by 2032. The report cites increasing availability of research funding, rapid technological advancements, and large-scale di...

In this article, Roche discusses a novel workflow for NGS library preparation that allows for much more efficient RNA-sequencing.

In this article, Roche Diagnostics elucidates upon some of their top tips and recommendations for anyone performing RNA-sequencing with degraded RNA inputs and demonstrate how to improve efficiency and performance.

/PRNewswire/ -- According to a recent study published by Future Market Insights, the lab accessories market is expected to reach US$ 1.1 Billion by 2032, up...