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Research led by Rajendra S. Apte, MD, PhD, in the John F. Hardesty, MD, Department of Ophthalmology & Visual Sciences at Washington University School of Medicine in St. Louis, is the focus of a $15 million pledge from philanthropist Jeffrey T. Fort to accelerate research and develop new treatments for diseases that cause vision loss.
Dry eye disease alters how the cornea heals itself after injury. Now, researchers have identified new potential therapy targets.
Studying mice, researchers at Washington University School of Medicine in St. Louis have found that proteins made by stem cells to help regenerate the cornea may become new targets for treating and preventing injuries to the cornea related to dry eye disease.
Those who suffer from dry eye disease are at greater risk of suffering injuries to their corneas. Researchers report proteins produced by stem cells that regenerate the cornea could be targeted to treat or prevent such injuries.
Injuries to the cornea are more likely to occur in people with dry eye disease than in people with healthy eyes.