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F. Hoffmann-La Roche Ltd: Phase III prevention trial showed subcutaneous administration of investigational antibody cocktail casirivimab and imdevimab reduced risk of symptomatic COVID-19 infections by 81%

F. Hoffmann-La Roche Ltd: Phase III prevention trial showed subcutaneous administration of investigational antibody cocktail casirivimab and imdevimab reduced risk of symptomatic COVID-19 infections by 81%
Placebo
Risk reduction
13
1.2
4 copies/mL)
14
0.4

Individuals without any COVID-19 symptoms who lived in the same household as an individual who tested positive to SARS-CoV-2 within the prior four days
. Based on the seronegative modified Full Analysis Set population, which includes all randomized subjects without evidence of current or prior SARS-CoV-2 infection (i.e., a negative RT-qPCR test and a negative antibody test) at randomization.
Adverse events (AEs) occurred in 20% (n=265 out of 1,311) of REGEN-COV participants and 29% (n=379 out of 1,306) of placebo participants, and serious AEs occurred in 1% (n=10) of REGEN-COV participants and 1% (n=15) of placebo participants. There were 0 REGEN-COV participants and 4 placebo pa ....

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Regeneron, Roche injectable antibody drug shows efficacy in preventing Covid-19

Regeneron, Roche injectable antibody drug shows efficacy in preventing Covid-19
A Regeneron Pharmaceuticals antibody cocktail currently authorized for treating Covid-19 now has additional clinical data showing it reduces the risk of infection spread. The drug developer, along with partner Roche, plan to ask regulators to expand the drug’s authorization to include disease prevention.
Shares0
A Covid-19 antibody cocktail developed by Regeneron Pharmaceuticals and Roche has pivotal clinical trial data showing it protected against the spread of infection among people in the same household. The results support use of the drug as a preventative measure in a formulation that’s easier for both physicians and patients. ....

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Man who started abusing girl after her First Holy Communion is jailed

Accused pleaded guilty to 33 counts of sexual assault which began when he was a teenager ....

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Regeneron's COVID-19 cocktail helps prevent symptomatic disease: study

3 Min Read
ZURICH (Reuters) -Regeneron is pursuing U.S. approval for its COVID-19 monoclonal antibody cocktail as a preventative treatment after it helped cut the risk of symptomatic infections in households where someone else is ill, the U.S. drugmaker said on Monday.
FILE PHOTO: The Regeneron Pharmaceuticals company logo is seen on a building at the company s Westchester campus in Tarrytown, New York, U.S. September 17, 2020. REUTERS/Brendan McDermid
REGEN-COV, a combination of casirivimab and imdevimab, protected household contacts from exposure to SARS-CoV-2, with 72% protection against symptomatic infections in the first week, and 93% after that, according to trial data released by the company. ....

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Cork bartenders to contest Covid-19 breach charges, court hears

Cork bartenders to contest Covid-19 breach charges, court hears
Two staff at Harp Bar charged with contravening regulations to limit spread of Covid-19
Mon, Apr 12, 2021, 21:44
Charges against the two bar staff in Cork are being brought under a section of the Health Act 1947 as amended by the Health (Preservation and Protection and other Emergency Measures in the Public Interest) Act 2020.

Two bartenders at a Cork city pub are to contest charges that they breached Covid-19 restriction regulations while working in the bar last summer.
Daniel Kiely (39) and Laura Leahy (27) are both charged with the Covid-19 regulation breaches, arising from alleged incidents at the Harp Bar on Pouladuff Road, Cork, in July 2020. ....

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