Sengenics' protein array to explore protein-protein interactions
This article outlines the study of protein-protein interaction that affects protein function using Sengenics protein array.
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This article outlines the study of protein-protein interaction that affects protein function using Sengenics protein array.
Excitation-contraction coupling (ECC) is the physiological process in which an electrical signal originating from the central nervous system is converted into muscle contraction. In skeletal muscle tissue, the key step in the molecular mechanism of ECC initiated by the muscle action potential is the cooperation between two Ca2+ channels, dihydropyridine receptor (DHPR; voltage-dependent L-type calcium channel) and ryanodine receptor 1 (RyR1). These two channels were originally postulated to communicate with each other via direct mechanical interactions; however, the molecular details of this c...
How researchers at the Chan Zuckerberg Biohub are mapping the human cell to generate an open-source, interactive library
How researchers at the Chan Zuckerberg Biohub are mapping the human cell to generate an open-source, interactive library
Biologists designed a screening method to understand how short stretches of amino acids — short linear motifs (SLiMs) — selectively bind to certain proteins, and distinguish between binding partners with similar structures.