Protein Binding News Today : Breaking News, Live Updates & Top Stories | Vimarsana

In the realm of water filtration and purification, the PES (Polyethersulfone) filter cartridge has gained significant attention as a...

In a new study, authors streamlined the quantification of protein binding kinetics without the need for elution or immobilization steps.

Biologists designed a screening method to understand how short stretches of amino acids — short linear motifs (SLiMs) — selectively bind to certain proteins, and distinguish between binding partners with similar structures.

The spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a pandemic due to the high transmission and mortality rate of this virus. The world health and economic sectors have been severely affected by this deadly virus, exacerbated by the lack of sufficient efficient vaccines. The design of effective drug candidates and their rapid development is necessary to combat this virus. In this study, we selected 23 antimicrobial peptides from the literature and predicted their structure using PEP-FOLD 3.5. In addition, we docked them to the SARS-CoV-2 spike protein receptor...

Key mutation sites in the SARS-CoV-2 spike protein modulate antibody and ACE2 affinity An allosteric center or site is one where a molecule other than the substrate to the protein can bind, altering the conformation of the protein. A paper recently uploaded to the preprint server bioRxiv* by researchers at Chapman University in California (Feb 22nd, 2021) utilized computational methods to screen severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mutants for affinity with the angiotensin-converting enzyme 2 (ACE2) receptor and monoclonal antibodies REG10987 and REG10933. The analysi...