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Tiziana Life Sciences : Announces Initiation of Clinical Trial in a Secondary Progressive Multiple Sclerosis (SPMS) Patient with Nasal Administration of Foralumab, a Fully Human Anti-CD3 Monoclonal Antibody, Under an Individual Patient Expanded Access Program (Form 6-K)


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Tiziana Life Sciences Announces Initiation of Clinical Trial in a Secondary Progressive Multiple Sclerosis (SPMS) Patient with Nasal Administration of Foralumab, a Fully Human Anti-CD3 Monoclonal Antibody, Under an Individual Patient Expanded Access Program

The first patient with SPMS was dosed on May 24, 2021 with nasally administered Foralumab. The treatment regimen will continue for six months to examine long-term safety, tolerability and clinical responses.

Previous clinical studies in healthy volunteers and COVID-19 patients showed that nasally administered Foralumab is well-tolerated with no apparent severe adverse events (SAEs) when dosed for up to 10 consecutive days. Results from these studies showed strong anti-inflammatory effects of the treatment regimen. ....

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Incyte Says Phase 3 TRuE-V Trial Met Primary And Key Secondary Endpoints


Incyte Says Phase 3 TRuE-V Trial Met Primary And Key Secondary Endpoints
WASHINGTON (dpa-AFX) - Incyte Corp. (INCY) announced Monday positive topline results from its pivotal Phase 3 TRuE-V clinical trial program evaluating the safety and efficacy of ruxolitinib cream, an investigational, nonsteroidal, anti-inflammatory, JAK inhibitor, topical therapy, in adolescent and adult patients (age ?12 years) with vitiligo.
Both the TRuE-V1 and TRuE-V2 studies met the primary endpoint, demonstrating that significantly more patients treated with ruxolitinib cream 1.5% twice daily (BID) achieved a ?75% improvement from baseline in the facial vitiligo area scoring index (F-VASI75) compared to patients treated with a vehicle control at Week 24. ....

District Of Columbia , United States , European Medicines Agency , Incyte Corp , Drug Administration , New Drug Application , மாவட்டம் ஆஃப் கொலம்பியா , ஒன்றுபட்டது மாநிலங்களில் , புதியது மருந்து விண்ணப்பம் ,