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Objective To summarize the breadth and quality of evidence supporting commonly recommended early childhood autism interventions and their estimated effects on developmental outcomes.

Design Updated systematic review and meta-analysis (autism intervention meta-analysis; Project AIM).

Data sources A search was conducted in November 2021 (updating a search done in November 2017) of the following databases and registers: Academic Search Complete, CINAHL Plus with full text, Education Source, Educational Administration Abstracts, ERIC, Medline, ProQuest Dissertations and Theses, PsycINFO, Psychology and Behavioral Sciences Collection, and SocINDEX with full text, Trials , and ClinicalTrials.gov.

Eligibility criteria for selecting studies Any controlled group study testing the effects of any non-pharmacological intervention on any outcome in young autistic children younger than 8 years.

Review methods Newly identified studies were integrated into the previous data ....

United States , Argyll And Bute , United Kingdom , New Jersey , Suzanne Albarran , Shannon Crowley Lapoint , Kristen Bottema Beutel , Kacie Dunham , Nicolette Caldwell , D Jonah Barrett , Jacobi Feldman , Tiffany Woynaroski , National Institutes Of Health , Jersey Autism Center , National Disability Insurance Scheme Of Australia , Vanderbilt Institute For Clinical , National Center , Behavioral Sciences Collection , National Institute For Health , Department Of Hearing , Human Services , Educational Administration Abstracts , Interagency Autism Coordinating Committee , Arkansas Association For Behavior Analysis , Translational Research , Us Department Of Health ,