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For the first time, researchers from the Wyss Institute for Biologically Inspired Engineering at Harvard University, Harvard John A. Paulson School of Engineering and Applied Sciences (SEAS), and Genentech<u>, a member of the Roche Group,</u> found a way to enhance and extend LN expansion, and study how this phenomenon affects both the immune system and efficacy of vaccinations against tumors. While the oversized LNs maintained a normal tissue organization, they displayed altered mechanical features and hosted higher numbers of various immune cell types that commonly are involved in immune responses against pathogens and cancers. Importantly, “jump-starting” lymph node expansion prior to administering a traditional vaccine against a melanoma-specific model antigen led to more effective and sustained anti-tumor responses in mice.
Lymph Node Expansion Enhances Vaccine Efficacy miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.
Each one of us has around 600 lymph nodes (LNs) – small, bean-shaped organs that house various types of blood cells and filter lymph fluid – scattered throughout our bodies.
Biomaterial vaccine enhances lymph node expansion following vaccination, boosting anti-tumor immunity medicalxpress.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from medicalxpress.com Daily Mail and Mail on Sunday newspapers.
NATURE publishes data on DUNP19 receptors role in cancer growth miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.
Dorrell Sees Growth In Buffs' Depth, Progress In Camp - University of Colorado Athletics cubuffs.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from cubuffs.com Daily Mail and Mail on Sunday newspapers.
Dorrell Sees Growth In Buffs' Depth, Progress In Camp - University of Colorado Athletics cubuffs.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from cubuffs.com Daily Mail and Mail on Sunday newspapers.
Webinar Series to Support Women R&D Leadership in Biotech Announced Share Article The Conference Forum announced a new four-part webinar series to support women R&D leadership in biotech from May 12 through August 26, 2021, virtually. “We are delighted to bring this webinar series to help support women R&D leaders in biotech and to encourage greater equity in biotech leadership,” Valerie Bowling, Executive Director, the Conference Forum. NEW YORK (PRWEB) April 23, 2021 The Conference Forum announced a new four-part webinar series to support women R&D leadership in biotech from May 12 through August 26, 2021, virtually. The first webinar will address navigating unconscious bias in the workplace. Panelists Ramani Varanasi of X-Biotix Therapeutics, Patricia Kitchen of Ocular Therapeutics, Dr Alison Schechter of Axcella, and Laurie Halloran of Halloran Consulting Group will discuss the realities of unconscious bias in the workplace, becoming aware of and dismantling microaggressions, dealing with an unpleasant boss and changing the culture as a leader in the workplace. This webinar will take place on May 12, 2021.