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Long-Term Outcomes of Sotorasib in KRAS-G12C Non–Small-Cell Lung Cancer

1. Sotorasib showed prolonged efficacy with a median OS of 12.5 months (33% at 24 months) and an ORR of 41% (50.6% of those remained in response at 12 months). 2. The safety profile of Sotorasib was favourable with common adverse events including diarrhea and hepatotoxicity. Evidence Rating Level: 2 (Good) Study Rundown: Sotorasib, an ....

Rating Level , Lung Cancers , Advanced Lung Cancer , Kras G12c , Chronic Disease ,

Roswell Parks Dr. Grace Dy Presents Long-Term Data on CodeBreaK 100 Sotorasib Study

Oncologist to share new data on KRAS inhibitor granted FDA approval for patients with non-small cell lung cancer. ....

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Novel Drug Proven Effective Against Mutated Lung Cancer

Tumor size in lung cancer patients who have a specific genetic error in the KRAS gene are reduced ....

Lung Cancer , Kras Gene , Rasg12c Inhibitor , Genetic Error , நுரையீரல் புற்றுநோய் ,

Huge breakthrough for oncology as scientists nail lung-cancer gene

For 40 years researchers have tried to block a mutant gene. They’ve now done so with a drug the FDA has approved ....

Fiona Rutherford , Robert Langreth , Drug Administration , Lung Cancer , Us Food And Drug Aministration , Kras G12c , Mirati Therapeutics , Richard Pazdur , பியோனா ரதர்ஃபோர்ட் , நுரையீரல் புற்றுநோய் , மிரட்டி சிகிச்சை ,

Amgen lands first FDA approval for drug targeting elusive mutation in lung cancer

FDA approval of Amgen drug sotorasib (Lumakras) makes the small molecule the first compound authorized by the regulator for treating cancers characterized by a KRAS G12C mutation. Mutated KRAS proteins had long been regarded "undruggable" targets. ....

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