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In Type 1 diabetes, verapamil prevents decline of IGF-1 and promotes beta-cell IGF-1 signaling

Published: August 25, 2023

These results add an additional, mechanistic aspect to further explain how the decades-old blood pressure medication verapamil can preserve beta cell function in Type 1 diabetes patients by affecting the hormone insulin-...

Source: uab.edu

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Cornell UniversityNew YorkUnited StatesBrian LuJunqin ChenPraveen SethupathyGuanlan XuEugenec GwaltneyWei Jun QianNational Institutes Of HealthDivision Of EndocrinologyDepartment Of Medicinedivision EndocrinologyDiabetes CenterDepartment Of MedicinePacific Northwest National LaboratoryMarnixe Heersink School Of MedicineNational Institute Of DiabetesDepartment Of Medicine Division EndocrinologyDiabetes ResearchDiabetes Research Center PilotUniversity Of Alabama At BirminghamStream DiabetesAnath ShalevMedicine DivisionNational Institutes