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New study uncovers effects of beer compound on cartilage cells in osteoarthritis

Formononetin (FNT), an isoflavonoid present in beer, was investigated for its effects on chondrocytes, the cells responsible for joint health. While low levels of FNT showed no harm and reduced inflammation, excessive exposure promoted catabolic responses, shedding light on the relationship between beer consumption and osteoarthritis risk. ....

Research Collaboratory , Protein Data Bank , Beer Polyphenol , Catabolic Effects , Image Credit , Natural Box , Structural Bioinformatics ,

Study identifies novel inhibitors against SARS-CoV-2 main protease

In a recent study posted to the bioRxiv server, researchers at the University of Arizona screened ~11 million severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease (MPro)-inhibiting small compounds in the ZINC15 database using a structure-based in-silico screening method. ....

Aimee Molineux , Neha Mathurnov , Neha Mathur , Research Collaboratory , Protein Data Bank , Lab Diagnostics Automation , University Of Arizona , Lab Diagnostics Automation Industry , Automation Industry Focus , Structural Bioinformatics , Coronavirus Disease Covid 19 , Ars Cov 2 , N Vitro , Evere Acute Respiratory , Evere Acute Respiratory Syndrome ,