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Safety and Preliminary Efficacy of Mesenchymal Stromal Cell... : Journal of the American Society of Nephrology lww.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from lww.com Daily Mail and Mail on Sunday newspapers.
Credit: Dana-Farber Cancer Institute In a major advance in the treatment of multiple myeloma, a CAR T-cell therapy has generated deep, sustained remissions in patients who had relapsed from several previous therapies, an international clinical trial has found. In a study posted online today by the New England Journal of Medicine, trial leaders report that almost 75% of the participants responded to the therapy, known as idecabtagene vicleucel (ide-cel), and one-third of them had a complete response, or disappearance of all signs of their cancer. These rates, and the duration of the responses, are significantly better than those produced by currently available therapies for patients with multiple relapses, according to investigators.