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Cell 'bones' mystery solved with supercomputers


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VIDEO: Subunits B (blue), B-1 (cyan), and B-2 (gray) depicted as ribbon diagrams. Initially bound to B-1, subunit B unflattens, straining contact between subunits until they separate. The resulting loose lateral.
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Credit: Vilmos Zsolnay, University of Chicago.
Our cells are filled with bones, in a sense. Thin, flexible protein strands called actin filaments help support and move around the bulk of the cells of eukaryotes, which includes all plants and animals. Always on the go, actin filaments constantly grow, shrink, bind with other things, and branch off when cells move.
Supercomputer simulations have helped solve the mystery of how actin filaments polymerize, or chain together. This fundamental research could be applied to treatments to stop cancer spread, develop self-healing materials, and more. ....

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Supercomputers Simulate 800,000 Years of California Earthquakes to Pinpoint Risks


Supercomputers Simulate 800,000 Years of California Earthquakes to Pinpoint Risks
Massive earthquakes are rare events and the scarcity of information about them can blind us to their risks, especially when it comes to determining the danger to a specific location or structure.
Scientists are now working to improve the calculations of danger by combining maps and histories of known faults with the use of supercomputers to simulate potential shaking deep into the future in California. The method is described in an article just published in the
Bulletin of the Seismological Society of America.
“People  always want to know: When is the next ‘Big One’ coming,” said coauthor Bruce Shaw, a seismologist at Columbia University’s Lamont-Doherty Earth Observatory. “Chaos always gets in the way of answering that question. But what we can get at is ....

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