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AE Management with CDK4/6 Inhibitors: Strategies for Treatment Continuity and Optimal Patient Outcomes

Medical professionals discuss proactive symptom management for adverse events like diarrhea, hair thinning, cytopenia, and neutropenia, offering guidance on dose reduction and treatment holds to optimize patient outcomes while minimizing adverse effects.

Optimizing-patient-outcomes , Stage-breast-cancer , Treatment-continuity , Optimal-patient-outcomes , Dose-reductions , Diarrhea , Tolerance , Imodium , Toxicity , Loperamide , Cytopenia

Real Time With Bill Maher

when you drink a soda, there's no fiber, there's no fat, there's no protein, no satiety hormones are being released. and in fact, hunger hormones get released when you eat these foods plus, they hack the dopamine center of your brain. >> they are chemically addictive as much as cocaine, cocaine, and nicotine okay. but first of all, i've read also the half the people who take ozempic are one of these three has no side effects, okay? right? mel, they will plateau. and we will plot term absolutely every single study illustrates that between weeks 68 and 70 to the drug stops working, build a tolerance to it so it becomes inevitable that you'll have to figure this out organically. >> anyway. and in addition, we really don't know what this looks like in perpetuity bill, people cannot get off of it and when they do all of the metrics have to be on it for life, for life, you will gain it all back and then some it's yo-yo dieting on crack.

Hunger , Brain , Satiety-hormones , Fact , Foods-plus , Protein , Fiber , Dopamine-center , Fat , Soda , People , Side-effects

Real Time With Bill Maher

also oh, bill, to regulate our appetite. >> but the issue is what's going to do it? healthy fats, protein, fiber, when you drink a soda, there's no fiber, there's no fat, there's no protein, no satiety hormones are being released. >> and in fact, hunger hormones get released when you eat these foods. >> plus, they hack the dopamine center of your brain. >> they are chemically addictive as much as cocaine, cocaine, and nicotine. >> okay. but first of all, i've read also the half the people who take ozempic are one of these three has no side effects, okay. right? mel, they will plateau. and we will play at absolutely. every single study illustrates that between weeks 68 and 72, the drug stops working, build a tolerance to it so it becomes inevitable that you'll have to figure this out organically anyway. and in addition, we really don't know what this looks like in perpetuity bill, people cannot get all have it and when they do all of the metal you have to be on it for life.

Issue , Bill , Protein , Hunger , Fact , Fiber , Satiety-hormones , Fats , Appetite , Soda , Fat , People

CNN Newsroom

understanding or making new question your understanding of how iran supreme leader ayatollah khomeini and the irgc is willing to go about things and carry out direct confrontations like well, i think there are two elements here. one is that there's clearly a much more tolerance for risk within the iranian leadership than was the case in the past. and this is partly reflective of the fact that the center of iranian politics has shifted to the right we have now much more altro hardliners at the decision-making centers in iran. and there's not a lot of voices of restraint left in the system, and that's reflective of the fact that iran is the only country in the world when the course of the past four months has targeted to nuclear weapons states, israel and pakistan but it's also reflective of the fact that iran's regional deterrence is network of partners and proxies in the region clearly did not stop israel from going after a senior iranian officials in

Things , Iran , Understanding , Confrontations , Supreme-leader , Irgc , Ayatollah-khomeini , Case , Leadership , Fact , Risk , Politics

CNN NewsNight With Abby Phillip

never hit around airspace. but in fact, least those cruise missiles. what was the ordinance on this? cruise missiles damage assessment on the ground, were there multiple engagements was this possibly massive amending ordinance penetrator, one of those deeply bombs that goes after a very deep target. the united states has those was it the mother of all bombs which we saw released a number of years ago in afghanistan. those have a very, because they're so large, about 30,000 pounds can they be released by aircraft? the israelis have currently in their inventory billie an f 15 that was equivalent appropriately, the empty wave. and if f 15 plus loaded weight underneath, you'd be right it out right at the hair in terms of the distance, the tolerance, and the ability to do that. but again, i mean these are all assumptions that we're making that will be pieced together

Fact , Airspace , Cruise-missiles , Assessment , Ordinance , Engagements , Ground , One , Number , United-states , Target , Bombs

The Last Word With Lawrence ODonnell

if they did carry out strikes inside of iran , that obviously would go against what joe biden had counseled them, which is to not directly retaliated against iranian territory. i think the u.s. has a greater degree of tolerance and understanding how this works. but even in the event in which the israeli government knows that the biden administration might not support this, they notify the united states. i think it is necessary to wait and see whether this is in conclusion of military action. is this a series of one-off strikes in iraq and syria and iran or is it the beginning of several strikes that could take place in different places? i think the u.s., before it comments in any formal way, would obviously want to know and be certain that this has been concluded. so i would expect to happen overnight.

Iran , Joe-biden , Territory , Rt-israel , Administration , United-states-government , Event , American , Works , Degree , Tolerance , Strikes

Laura Coates Live

well, in this specific situation, like you said at the top, this is a cardinal sin. this is something adam silver then may commissioner, he had the right of jurisdiction to really conduct any type of discipline that he wanted. he could have suspended jontay porter for games. you could suspended him for a year, two years. he chose to issue a i've time ban in the nfl. players have been suspended for betting on nfl games. they've gotten about a year and sometimes even get reduced penalty. but in the nba, it's been made clear, it's a message that everyone around the league got today from players to coaches, to every executive around the league. they understand betting on games in the nba. the wnba, or the nba. g league, it is absolutely a no tolerance policy. you will be banned for life and that's what happened with jontay porter and the nba's has also given all of their evidence to the federal investigators that were taking

Something , Type , Top , Situation , Adam-silver , Cardinal , Commissioner , Sin , Jurisdiction , Players , Games , Jontay-porter

The Source With Kaitlan Collins

just reposted it without comment. he has done that a couple of times and i think i called it out on the show earlier. i said da's office needs to stop that because it's essentially him making the statement, but they have not done that and now trump's taking it to the next level where he's retyping something that a media figures said and then sending that out. i think that violates the gag order. and here's the thing. the most sensitive group of people here that people who need to be protected most, or the juror. >> so if i'm the judge, i have the least tolerance for anything that might interfere with the jury what does the judge do he knows what he has here as a political case, it's a legal case, but it's a political case and he's tried to give trump's some elasticity and sort of stretch maybe where the line is, how far can you let him go and maintain order in his courtroom? >> i think he's given an amazing amount of leeway and in that sense, we hear trump talking about him being treated differently. he's getting a benefit here because the judge is not holding his feet to the fire because he's trying to be as balanced as he can because

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Laura Coates Live

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