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"Insignoic acids A – E, unusual α, β-unsaturated keto fatty acids isola" by Ritesh Raju, Paayal Kumar et al.

Anti-inflammatory bioassay-guided compound isolation from the exocarp of the Australian rainforest tree Endiandra insignis (family Lauraceae) has led to the discovery and structural elucidation of unusual α, β-unsaturated twenty-four carbon fatty acids and their positional isomers, insignoic acids A – E (1a – 5c). The stereochemistry and position of the double bond within the aliphatic chain were independently determined via NMR spectroscopy and Ozone-Induced Dissociation (OzID) Mass Spectrometry, respectively. Compounds (1a – 5c) displayed good to moderate anti-inflammatory activity in the range of 8–84 μM. The low therapeutic index observed when assessing the cell viability in the RAW macrophage cell lines, prompted us to investigate the anticancer potential of these unusual fatty acids. The anti-cancer activity was assessed in A-431 carinoma cell lines and MM649 melanoma cell lines. Insignoic acid C (3a-f) exhibited the highest level of potency with an IC50 value of 5–7 ....

Ozone Induced Dissociation , Mass Spectrometry , Anti Cancer , Anti Inflammatory , Nsignoic Acids , Unsaturated Fatty Acids ,

Animal Fats And Oils Market to Surpass $475.58 Billion, Globally, by 2030 at 7.9% CAGR: Coherent Market Insights (CMI)

Animal Fats And Oils Market to Surpass $475.58 Billion, Globally, by 2030 at 7.9% CAGR: Coherent Market Insights (CMI)
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7 Anti-Inflammatory Snacks You Can Add To Your Diet In 2023

Discover great anti-inflammatory snacks with antioxidants and additional nutrients to boost your health and reduce inflammation in 2023 . ....

District Of Columbia , United States , Bajro Sari , Karem Fouda , Youssef El Rayess , Palanisamy Arulselvan , Sivapragasam Gothai , Khadijeh Mirzaei , Clemens Wittenbecher , Elise Adrian Ostrander , Pervin Monira , Alain Abi Rizk , Masoumeh Tangestani Fard , Rebecca Elisabeth Meister , Yuksel Altuntas , Mamoru Isemura , Farideh Shiraseb , Jelena Popovi , Waliza Ansar , Lukas Schwingshackl , Domenico Maurizio Toraldo , Tomokazu Ohishi , Afraa Jabakhanji , Esraa Keewan , Javad Sharifi Rad , Jordi Salas Salvad ,

7 Anti-Inflammatory Snacks You Can Add To Your Diet In [AU] 2023

Discover great anti-inflammatory snacks with antioxidants and additional nutrients to boost your health and reduce inflammation in 2023 . ....

United States , District Of Columbia , Alain Abi Rizk , Masoumeh Tangestani Fard , Bajro Sari , Karem Fouda , Sivapragasam Gothai , Palanisamy Arulselvan , Youssef El Rayess , Elise Adrian Ostrander , Clemens Wittenbecher , Khadijeh Mirzaei , Pervin Monira , Norhaizan Mohd Esa , Egeria Scoditti , Chandrakala Aluganti Narasimhulu , Kyoung Hong , Indika Edirisinghe , Raviella Zgheib , Sharida Fakurazi , Jephat Chifamba , Thandi Puoane , Katarzyna Neffe Skoci , Dorota Zieli , Mireia Urpi Sarda , Yuksel Altuntas ,

7 Anti-Inflammatory Snacks You Can Add To Your Diet In [UK] 2023

Discover great anti-inflammatory snacks with antioxidants and additional nutrients to boost your health and reduce inflammation in 2023 . ....

District Of Columbia , United States , Farideh Shiraseb , Mamoru Isemura , Yuksel Altuntas , Rebecca Elisabeth Meister , Lukas Schwingshackl , Domenico Maurizio Toraldo , Waliza Ansar , Jelena Popovi , Javad Sharifi Rad , Esraa Keewan , Afraa Jabakhanji , Tomokazu Ohishi , Marc El Beyrouthy , Patricio Lopez Jaramillo , Aleksandra Krsti , Jordi Salas Salvad , Egeria Scoditti , Chandrakala Aluganti Narasimhulu , Norhaizan Mohd Esa , Jephat Chifamba , Sharida Fakurazi , Raviella Zgheib , Thandi Puoane , Kyoung Hong ,