Some social issues in DYRK1A model mice stem from faulty inhibitory circuits
Alterations in inhibitory circuits and difficulties in social recognition characterize mice missing one copy of DYRK1A, a gene linked to autism.
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Alterations in inhibitory circuits and difficulties in social recognition characterize mice missing one copy of DYRK1A, a gene linked to autism.
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When exploring a new environment, mice make use of a unique long-distance connection in the brain that prompts them to pay attention to the most salient features of the environment, according to new UCSF research.
When exploring a new environment, mice make use of a unique long-distance connection in the brain that prompts them to pay attention to the most salient features of the environment, according to new research from UC San Francisco. The link, originating in the prefrontal cortex and stretching to the hippocampus, provides evidence of how the brain's higher cognitive regions refine operations occurring in distant brain areas.