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Tiam1 inhibition mitigates morphine tolerance and hyperalgesia in mouse model - Vimarsana News

Tiam1 inhibition mitigates morphine tolerance and hyperalgesia in mouse model

Morphine and other opioids are vital to treat severe and chronic pain. However, they have two problems -; prolonged use creates morphine tolerance, where ever-increasing doses are needed for the same pain relief, and paradoxically, prolonged use also can create an extreme sensitivity to pain, called hyperalgesia.

Here's where BlackRock sees investment opportunities as the population ages - Vimarsana News

Here's where BlackRock sees investment opportunities as the population ages

Populations are aging in some markets and growing in others. That brings selective investment opportunities, says BlackRock.

Source: cnbc.com
Ensuring safety in next-gen foods - Vimarsana News

Ensuring safety in next-gen foods

Novel proteins present food safety concerns posed by pathogens and more.

Morphine tolerance results from Tiam1-mediated maladaptive plasticity in spinal neurons - Vimarsana News

Morphine tolerance results from Tiam1-mediated maladaptive plasticity in spinal neurons

Understanding the mechanisms underlying tolerance and hyperalgesia is essential to enhance morphine’s utility in chronic pain management. Understanding the mechanisms underlying tolerance and hyperalgesia is essential to...

Source: uab.edu
Bonds Drop as Traders Trim Rate-Cut Expectations: Markets Wrap - Vimarsana News

Bonds Drop as Traders Trim Rate-Cut Expectations: Markets Wrap

(Bloomberg) — The world’s biggest bond market kicked off the week on the back foot as geopolitical pressures abated and traders positioned for this week’s key inflation data. Treasuries fell across the curve, with 10-year yields hitting the highest levels since November and coming within a striking distance of the 4.5% level that some investors…