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Natural Killer (NK) Cell Therapy Pipeline Research Report

Dublin, April 19, 2024 (GLOBE NEWSWIRE) -- The

Dublin , Ireland , Sweden , Pharma-monalizumab , Kiadis-pharma , Persongen-biotherapeutics , Route-of-administration , Cellprotect-nordic-pharmaceuticals , Altor-bioscience-corporation , Vecura-at-karolinska-university-hospital , Karolinska-university-hospital-in-huddinge , Natural-killer

Household chemicals endanger brain's myelin-forming cells

Study uncovers how environmental chemicals, specifically organophosphate flame retardants and quaternary compounds, negatively affect oligodendrocyte development, implicating them in potential neurodevelopmental risks such as ADHD and autism, by employing an innovative high-throughput screening approach on mouse and human stem cell-derived models.

United-states , International-society-for-stem-cell-research , National-health , National-institutes-of-health , Nutrition-examination-survey , Case-western-reserve-university-institutional-animal-care , United-states-environmental-protection-agency , Nature-neuroscience , Hyperactivity-disorder , International-society , Stem-cell-research

ABT199/venetoclax synergism with thiotepa enhances cytotoxicity of chemo drugs in AML cells

A new research paper was published in Oncotarget's Volume 15 on March 14, 2024, entitled, "ABT199/venetoclax synergism with thiotepa enhances the cytotoxicity of fludarabine, cladribine and busulfan in AML cells."

Texas , United-states , Borjes-andersson , Uday-popat , Benignoc-valdez , Yago-nieto , David-murray , Jeremyl-ramdial , University-of-texas-md-anderson-cancer-center , University-of-alberta , Bin-yuan , Cancer-center

The importance of mitochondrial toxicity assessment

Agilent Technologies highlights the importance of assessing mitochondrial toxicity

Agilent-technologies , Application-note , Mitochondrial-toxicity , Rug-discovery , Rug-development , N-vitro , Ytotoxicity , Lu-gal , Iochemical ,

Natural killer cells lead the charge in cancer treatment innovation

Review synthesizes research on NK cells' role in cancer immunity and their potential in therapeutics through bioengineering, immune checkpoint inhibitors, and cell engagers, highlighting ongoing preclinical and clinical trials.

Cancer , Ancer-treatment , Atural-killer-cells , Ioengineering , Lood , One , One-marrow , Art-cell , Ell , Ytokine , Ytotoxicity

Enhanced transfection efficiency: Protein-coated microplates

Transfection efficiency in HepG2, CHO, and HEK-293 cells was assessed using CELLCOAT plates and reporter plasmids

Greiner-bio , Application-note , Greiner-bio-one-gmbh , Transfection , Ell-culture , Ytotoxicity , Icroplates , Rotein-coating ,

Curcumin spray shows promise in fighting SARS-CoV-2 and flu viruses

A study in the Virology Journal reveals a curcumin-containing oro-nasal film spray with potential antiviral activity against SARS-CoV-2 and influenza viruses, boosting mucosal immunity without cytotoxic effects.

Thailand , Sanchari-sinha-dutta , Coronavirus-disease-covid-19 , Urcumin , Lu , Ars , Ars-cov-2 , Nti-inflammatory , Ntioxidant , Ssay , Ell

Deep learning unlocks new antibiotic classes, revolutionizing the fight against resistance

A Nature journal study employs deep learning to analyze chemical sub-structures, leading to the discovery of new structural classes of antibiotics, showcasing the potential of AI in accelerating antibiotic development.

Drug-repurposing-hub , Deep-learning , Ntibiotic , Ntibiotic-resistance , Ompound , Ytotoxicity , Volution , Luoroquinolone , Igh-throughput-screening , Achine-learning , Olecule

New lipidic peptide IK14004 shows promise in treating cancer and reducing autoimmune complications

A lipidic peptide, named IK14004.

Scientific-reports , Cancer , Utoimmune-disease , Utoimmunity , Ancer-treatment , D4 , Ell , Ell-death , Ytokines , Ytotoxicity , Xhaustion

Next-generation ovarian cancer therapy: Engineered Vδ2 T cells show promise in preclinical trials

A prospective path for allogeneic cellular immunotherapies.

Nature-communications , Cancer , Ancer-therapy , Varian-cancer , Reclinical , Dcc , Ntibody , Ntigen , Lood , Arcinoma , Ell